Histopathological Correlation of Time Signal Intensity Curve in MRI Detected Breast Lesions
Journal Title: International Journal of Medical Research Professionals - Year 2017, Vol 3, Issue 3
Abstract
Introduction: Dynamic contrast enhanced MR imaging of breast characterizes the lesions more accurately than morphological parameters which helps in to distinguish between benign and malignant lesions. Aims: To differentiate benign from malignant breast lesions detected on MRI by analyzing quantitative lesion characteristics. To compare and correlate the radiological diagnosis with the final histopathological diagnosis. Materials and Methods: A prospective study on 41 cases was conducted in the department of Radiodiagnosis, Government Medical College, Kozhikode during the period from Aug 2009 to July 2010 who were undergoing MRI of breast for characterization of lesions. Contrast enhancement Initial and post initial kinetics were plotted on a graph to get the time signal intensity curve which was studied and correlated with the final histopathological diagnosis. Results: Of the total 41 cases, 48.8% were malignant and 51.2% were benign. 38.1% of the benign lesions showed <50% initial enhancement while no malignant lesions showed this. 80% of malignancies demonstrated strong (>100%) initial enhancement. 20% of malignant lesions and 28.6% of benign lesions demonstrated moderate (50-100%) initial enhancement. Continuous post initial kinetics was noted in 66.7% of benign lesions and none of the malignant lesions. 95% of malignancies showed washout kinetics. Plateau kinetics was shown by 5% of malignant and 9.5% of benign lesions Conclusion: Malignant lesions more frequently showed >100% initial kinetics and type III (wash out) post initial kinetics; however, an overlap exists.
Authors and Affiliations
Juvaina. P, Gomathy Subramaniam, V. R. Rajendran, P. Rajan, Naufal. P
Keywords
Related Articles
- EP ID EP547794
- DOI 10.21276/ijmrp.2017.3.3.015
- Views 100
- Downloads 0
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