Histopathological Spectrum of Vesiculobullous Lesions of the Skin: Study at a Tertiary Care Hospital
Journal Title: International Journal of Medical Research Professionals - Year 2018, Vol 4, Issue 4
Abstract
Background: Vesiculobullous lesions are one of the predominant groups of skin lesions. They are the primary morphological patterns of skin reaction to various external and internal pathologic stimuli. Various types of pathologic processes can lead to development of vesiculobullous eruptions over body. Methodology: This observational study was conducted in Department of pathology and department of dermatology. 72 patients who presented with vesiculo bullous lesions of skin not related to infectious aetiology were enrolled for the study. Clinical details and histopathological findings were analyzed. Results: Pemphigus group of disease comprised the major proportion comprising 38 cases (52.9%), out of which 31 cases were pemphigus vulgaris (43.1%), 4 cases were pemphigus foliaceus (5.6%) and 3 cases were pemphigus vegetans (4.2%). Bullous pemphigoid was the second most common type and was found in 10 biopsies (13.9%). Conclusion: Punch biopsy of the skin is a simple, inexpensive, safe OPD procedure, causing minimal discomfort to the patient. Histopathological features are conclusive in majority of vesiculobullous lesions of skin; thus it forms the primary diagnostic modality in the management of such patients where the facility for immunoflourescence technique is not available.
Authors and Affiliations
Ashutosh Kumar, Ankita Mittal, Rashmi Chauhan, Faiyaz Ahmad, Seema Awasthi, S. Dutta
Keywords
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- EP ID EP535494
- DOI 10.21276/ijmrp.2018.4.4.058
- Views 93
- Downloads 0
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