History of research on depression: biomolecular considerations and philosophical reflections
Journal Title: New Medicine - Year 2010, Vol 14, Issue 4
Abstract
Recent studies have demonstrated the existence of significant differences in fatty acid composition of the cell membranes of platelets between depressed humans and apparently healthy subjects.These differences were identified through the use of advanced mathematical tools. In particular an artificial neural network (ANN), the Self-Organizing Map (SOM) described by Kohonen (1982), was employed. The SOM isolated three fatty acids, arachidonic acid (AA), linoleic acid (LA) and palmitic acid (PA), and was able to map two different populations (normal and depressive), recognizing as similar subjects belonging to the same population.The work summarizes the main aspects that link platelets, brain and serotonin through lipid cell membrane viscosity.This seems to be, today, one of the most fascinating hypotheses in the interpretation of depressive disorder. The present work concludes with philosophical reflections about the new feature of technological depression.
Authors and Affiliations
Massimo Cocchi, Lucio Tonello, Fabio Gabrielli, Sofia Tsaluchidu
Keywords
Related Articles
- EP ID EP55196
- DOI -
- Views 158
- Downloads 0
Representations of the social body and drug use
Aim. In our research we studied the connections between the body culture and drug using behaviour. Material and Method. An empirical, survey-kind of analysis was carried out; the questionnaire contains a list of question...
The efficacy of antibiotic therapy in the treatment of complicated acute sinusitis in children – the initial report
<b>Introduction. </b>Acute ethmoid sinusitis in children can result in severe complications. The treatment consists of antibiotic therapy and in certain cases surgery is mandatory. <br&...
Guz Buschkego-Lowensteina. Operacja wycięcia okrężnego guza okolicy odbytu z pokryciem ubytków przesuniętymi płatami anodermalnymi – opis przypadku
Social support for people suffering from depression and their families
The experience of mental illness is a difficult situation not only for the patient but also his or her family. Natural consequences of this morbid state include changes of past lifestyle and social functioning of patient...
The detection of specific antibodies against B. burgdorferi s.s., B. afzelii , B. garinii, and B. spielmani antigens in patients with Lyme disease in eastern PolandThe detection of specific antibodies against B. burgdorferi s.s., B. afzelli, B. garinii and B. spielmani antigens
Aim: The purpose of investigation was to determine the presence of antibodies for B. burgdorferi s.s., B. afzelii, B. garinii and B. spielmani in persons with Lyme disease from the Lubelski region (Eastern Poland) in the...