HIV/TB co-infection in the structure of legal pathology diseases in HIV-popular persons (based on materials of the medical archive of the Regional Clinical Infectious Diseases Hospital of Kharkiv for the period 2013—2017)
Journal Title: Туберкульоз, легеневі хвороби, ВІЛ-інфекція - Year 2019, Vol 0, Issue 2
Abstract
Objective — to determine the incidence of HIV/TB co-infection in the structure of the disease in pulmonary pathology, to describe the clinic and the diagnostic features of HIV-associated tuberculosis, depending on the level of immunosuppression, and to highlight the difficulties of diagnose in early detection of tuberculosis in HIV-positive individuals who were on treatment at Regional Clinical Infectious Diseases Hospital for the period 2013—2017. Materials and methods. A retrospective analysis of the data of the medical record of the OKIL of Kharkiv city for the period of 2013—2017 was conducted. 78 histories of HIV-infected patients who came from the pathology of the lungs, the final diagnosis of which was tuberculosis, were analyzed. Informative method of standard diagnostic methods of TB infection in HIV-positive persons in the hospital of OKIL is determined. Statistical data processing was performed by methods of variation and correlation statistics using software. Results and discussion. A fourfold increase in the number of cases of pulmonary tuberculosis among HIV-infected persons during the study period, which was referred to the hospital OKIL, was revealed. All persons were able-bodied age, male dominated by gender. 56 % of the patients had a drug dependence in the past, 33 % — consumed alcohol, 77 % — smoked. Only 15 % of patients received ART. The main clinical manifestations were intoxication syndrome, mucociliary in sufficiency syndrome and focal condensation of pulmonary issue. The most informative method of standard diagnosis of tuberculosis was cultural (54 %).The X-ray method in the diagnosis of tuberculosis was informative in 27 % of cases. Conclusions. The increase in the number of cases of tuberculosis against HIV, in adequate coverage of HIV-positive people with ART and insufficiently informative of standard methods of diagnosis of mycobacterial infection in HIV-infected people leads to the invention of new ones or to the improvement of existing techniques. All patients with lung lesions on the background of HIV to confirm their tuberculosis are in the hospital of the acute medical accident without receiving etiotropic treatment and endangering the risk of infection with mycobacterium tuberculosis of other immunodeficiency patients and medical staff.
Authors and Affiliations
O. V. Tsiko
Keywords
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- EP ID EP674605
- DOI 10.30978/TB2019-2-78
- Views 92
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