Homocysteine level in Coronary artery disease patients of Ahmedabad population
Journal Title: International Journal of Medical Science and Public Health - Year 2017, Vol 6, Issue 3
Abstract
Background: Coronary artery disease (CAD) is a major cause of morbidity and mortality in the modern society. The cost of managing CAD is a remarkable economic burden and so prevention of CAD is very essential step in its management. The majority of CAD patients have at least one cardiovascular risk factor, but 20% of them have no traditional risk factors. Persistent focus on newer risk factors is necessitate as they may further step forward our ability to predict future risk and determine treatment. Recently, homocysteine has been recognized as a risk factor for CAD. This study was conducted to find out the homocysteine as one of the risk factors of CAD in population of Ahmedabad. Objective: The aim of this study is to categorize homocysteine as a risk factor for CAD and to find out the effect of age on homocysteine level. Materials and Methods: Totally, 100 patients with CAD and 100 normal controls were included in study and homocysteine concentration is measured using standard reagent kit on Abbott AxSYM close system. Result: 78% of patients in the study group and only 5% of participants in control group have high homocysteine level above biological reference interval, and its concentration was significantly high in study group patients compared to the normal control group participants (33.02 ± 17.41 and 13.88 ± 3.86 respectively, P < 0.001). There was a significant positive correlation between homocysteine and age is observed. Conclusion: Increase homocysteine level may be one of the risk factor of CAD in young age. Homocysteine level is increases with growing age and play a role in the occurrence of CAD.
Authors and Affiliations
Jatin D Patel, Kirankumar P Chauhan, Chandan Chakrabarti, Hiran I Sanghani
Keywords
Related Articles
- EP ID EP308548
- DOI 10.5455/ijmsph.2017.0956213102016
- Views 73
- Downloads 0
Traditional clinical examination vs objective structured practical examination in human physiology: Examiner's bias
Background: A traditional clinical examination (TCE) in physiology focuses on the “knows ” and “knows how” aspects and is inadequate in evaluating the overall performance of the students. Objective structured pra...
Krait snakebite mimicking brain death: a case report from central India
Snakebite is a common medical emergency in India. Cobra ( Naja naja ) and common krait ( Bungarus caeruleus ) are important neurotoxic snakes causing neuroparalysis. We are reporting a pediatric case report of krai...
Prevalence of depression and its determinants among elderly population in a rural area of Kanchipuram district, Tamil Nadu
Background: Globally, the proportion of elderly population is in rise, and as age advances, there is an increased morbidity and disability. Depression is the most usual mental disorder in the elderly, but usually under d...
Impact of cardiopulmonary resuscitation training in 1st year of MBBS
Background: The present medical education system fails to inculcate appropriate skills and competence to the students to serve the community. As the world is moving toward the system of “need-based education,” the traini...
Morbidity profile of children residing in orphanages - A cross-sectional study in Chitradurga, Karnataka
Background: Orphans and vulnerable children (OVC) are a group of underprivileged population in society. They do not receive proper physical and emotional care because they are unaccompanied, displaced, and lacking family...