Hospital Antibiogram: A Necessity in Monitoring Sensitivity of Isolates and Rationale Use of Antibiotics’
Journal Title: Microbiology Research Journal International - Year 2016, Vol 13, Issue 3
Abstract
Background: The laid protocols by CDC (center for disease control) narrated the dire need of local anti-biograms. Therefore the current study had been planned to acquire the knowledge about sensitivity pattern of various isolates in different specimens. Objectives: To identify the local antibiotic sensitivity data against various isolates from different specimens. Materials and Methods: A descriptive cross sectional study was conducted at the Pathology department of Al Nafees Medical College & Hospital, Islamabad, Pakistan. The duration of study was 04 months i.e 01st June to 01st Oct. 2015. Frequencies and percentages were the numerical variables extracted by using the SPSS version 16. Results: A total of 336 different specimens were received during study period. E. coli is commonest organism isolated from urine, high vaginal swabs (HVS) and Pus i.e. 60.60%, 100% and 25% respectively. Klebsiella species is the second most common organism (12.12%) followed by Pseudomonas (9.09%) isolated from urine. E. coli, Klebsiella, Pseudomonas and Staphylococcus aureus were isolated at same frequency (25%) from pus. Salmonella typhi was isolated from blood (100%). The drugs of choice for E. coli are quinolones and aminoglycosides by showing the sensitivity of about 75% each. For Klebsiella pneumoniae, the ideal antibiotics are aminoglycosides (85.1%) and 2nd generation cephalosporins (85%). For Pseudomonas aeruginosa, extended spectrum penicillin, quinolones, 2nd and 3rd generation cephalosporins are the most suitable ones showing the sensitivity of 100% each. Conclusion: Quinolones, aminoglycosides, 2nd and 3rd generation cephalosporins are the drugs of choices for the treatment of many gram positive and gram negative infections.
Authors and Affiliations
Ishtiaq Ahmend, Humaira Zafar, Noor Khan Lakhnana, Sundas Ishtiaq, Kiran Tauseef, Mudassira Zahid, Ahsan Kazmi
Keywords
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- EP ID EP350859
- DOI 10.9734/BMRJ/2016/23795
- Views 92
- Downloads 0
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