Hotspots and challenges in blocking the mother-to-child transmission of hepatitis B virus
Journal Title: Journal of Clinical Hepatology - Year 2024, Vol 40, Issue 11
Abstract
Chronic hepatitis B virus （HBV） infection remains a major public health challenge in China， affecting over 70 million people and posing great challenges to the prevention and control of the disease. At present， both the government and sectors of the society are making efforts to achieve the goal of eliminating viral hepatitis as a public health threat by 2030. Mother-to-child transmission is the main route of transmission of HBV， and therefore， blocking the mother-to-child transmission of HBV is the key link in eliminating viral hepatitis. At present， several critical issues still remain unresolved， including the long-term safety of tenofovir alafenamide fumarate during pregnancy， the safety of antiviral therapy in early pregnancy， the effectiveness of immunoglobulin-free strategy， and the risk of HBV transmission through germ cells. Addressing these challenges is important for promoting the blocking of the mother-to-child transmission of HBV and accelerating the progress toward the 2030 goals.
Authors and Affiliations
Xueru YIN, Ruixuan HONG, Zhihua LIU, Jinlin HOU
Keywords
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- EP ID EP753510
- DOI 10.12449/JCH241102
- Views 33
- Downloads 1
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