https://jms.yeniyuzyil.edu.tr/hemsirelik-ogrencilerinin-elestirel-dusunme-becerilerinin-karar-verme-ve-empati-becerileri-arasindaki-iliskinin-incelenmesi/
Journal Title: Yeni Yuzyil Journal of Medical Sciences - Year 2022, Vol 3, Issue 2
Abstract
Aim: The current increase in the rate of nosocomial infection caused by the drug-resistant and multi-drug resistant (MDR) Gram-negative bacteria rendered the current treatment options insufficient. In this case-control study, we aimed to determine the risk factors for drug-resistance, multi-drug resistance and mortality in nosocomial bloodstream infections (NBSIs). Material and Methods: The study included one hundred consecutive patients aged 18 years and over with nosocomial bloodstream infections caused by Gram-negative bacteria. Twenty-nine patients with multidrug-resistant Gram-negative bacteremia constituted the case group, and 71 patients without MDR constituted the control group. Forty-four patients who ended up with mortality formed the case group, and 56 patients who recovered formed the control group. Results: Acinetobacter baumannii was isolated as the most common causative microorganism. The mean age in the group with MDR bacteria-caused NBSI was significantly higher than in the non-MDR group (p=0.02). Older age (Odds ratio [OR] = 1.0; 1.0-1.1; p=0.047), acute renal failure (ARF) (OR= 12.8; 2.7-58.7; p=0.001), use of cephalosporins within the last month (OR= 15.8; 2.3-107.6; p=0.005), and A. baumannii as the causative agent (OR=6.1; 1.6-23.8; p=0.008) were independent risk factors for development of MDR bacteria-caused NBSI. In patients with Gram-negative bacteremia; malignancy (OR=7.7; 2.4-24.4; p <0.001), high Eastern Cooperative Oncology Group (ECOG) score (OR=2.9; 1.3-6.5; p=0.009), and high Acute Physiological and Chronic Health Evaluation II (APACHE II) score (OR=1.2; 1.1-1.3; p=0.001) were found to be independent risk factors for mortality. Discussion and Conclusion: The findings of the present study revealed that advanced age, acute renal failure, and use of cephalosporins within the last month were independent risk factors for multidrug resistance in nosocomial Gram-negative bacteremia. The findings§ also revealed that malignancy, high ECOG and APACHE II scores were independent risk factors for mortality in patients with nosocomial Gram-negative bacteremia. Avoidance of empiric use of broad-spectrum cephalosporins may limit resistance. In addition, considering existing risk factors when initiating empiric therapy may prevent poor prognosis.
Authors and Affiliations
Tuba KURUOĞLU, Şaban ESEN
Keywords
Related Articles
- EP ID EP713799
- DOI https://doi.org/10.46629/JMS.2022.84
- Views 70
- Downloads 0
Evaluation of Dentists' Awareness of The COVID-19 Pandemic, Attitudes, and Behaviors Regarding Infection Control, and Anxiety Levels by Specialty and Gender
Aim: Coronavirus disease (COVID-19), declared a pandemic by the World Health Organization, poses a major threat to healthcare professionals. This study aims to evaluate knowledge levels about the Covid-19 pandemic, at...
Covid-19 Hastalığı ve Fiziksel İnaktivitasyon
2020 yılı, Çin’in Hubei eyaletinin başkenti Wuhan şehrinden başlayan ve tüm dünyayı etkisi altına alan SARS-CoV-2 virüsünün neden olduğu COVID-19 hastalığı ile başlamıştır. Dünya Sağlık Örgütü tarafından 11 Ma...
Anestezi Türünün Ameliyat Öncesi Anksiyete Düzeyine Etkisinin Belirlenmesi
Amaç: Araştırma, elektif cerrahi hastalarına uygulanacak olan anestezi türünün, hastaların ameliyat öncesi anksiyete düzeylerine etkisini belirlemek amacıyla planlandı. Gereç ve Yöntem: Tanımlayıcı türdeki araştı...
COVID-19’da D Vitamininin ve Eczacının Rolü
virüsünün sebep olduğu yüksek patojenite ve bulaştırıcılığa sahip bir solunum yolu hastalığı olarak bilinmektedir. Bu hastalık Dünya Sağlık Örgütü (DSÖ) tarafından 11 Şubat 2020 tarihinde COVID-19 adını almıştı...
Bağımlı Bireylerin Yaşadıkları Ruhsal Sorunlar ve Önlemeye Yönelik Uygulamalar
Bağımlılık, alkol ya da diğer maddelerin kullanımına bağlı psikososyal, biyokimyasal faktörlerin etkilediği bir durumdur. Gün geçtikçe yaygınlaşan bağımlılık; bireylerde duygudurum, anksiyete, kişilik bozuklukları gibi...