HUMAN CHROMOSOMAL Q-HETEROCHROMATIN POLYMORPHISM AND ITS RELATION TO BODY HEAT CONDUCTIVITY
Journal Title: International Journal of Genetics - Year 2014, Vol 6, Issue 1
Abstract
It is found that approximately 15-20% of non-coding part of human DNA is constitutive heterochromatin. There are two types of constitutive heterochromatin: C- and Q-heterochromatin. C-heterochromatin regions (C-HRs) are found in the genome of all higher eukaryotes, while Q-heterochromatin regions (Q-HRs) are only in the genome of three higher primates (Homo sapiens, Pan troglodytes and Gorilla gorilla). Human chromosomes possess both types of constitutive heterochromatin. In man C-heterochromatin is present in all his chromosomes, varying mainly in size, while Q-heterochromatin can only be detected on seven autosomes and the Y-chromosome. In this case individuals in a population differ from each other on the number, location, size and intensity of staining (fluorescence) of chromosomal Q-HRs. However, the question of possible biological role of chromosomal Q-HRs in human life remains open. A hypothesis that amount of Q-HRs in genome is possibly connected with human body thermal conductivity (BHC) has been proved. Results obtained show that individuals in population truly differ from each other in BHC and its level depends on the amount of chromosomal Q-HRs in human genome. The question of place and possible role of human BHC in norm and pathology is also being discussed.
Authors and Affiliations
A. I. IBRAIMOV, A. A. AKANOV, T. S. MEIMANALIEV, K. O. SHARIPOV, R. D. SMAILOVA, R. DOSYMBEKOVA
Keywords
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