Hygienic assessment of toxicodynamics peculiarities and mechanism of action of oxyacetamide class herbicide (flufenacet) on homoiotherms and human body
Journal Title: Український журнал сучасних проблем токсикології - Year 2017, Vol 77, Issue 1
Abstract
Analysis of literature data regarding toxic properties of a new oxyacetamide class herbicide, flufenacet, in acute, subchronic, and chronic experiments among different species of animals was performed. It was established that according to the hygienic classification of pesticides (DSanPin (State sanitary norms and rules) 8.8.1.002-98), flufenacet belongs to the class 2 of hazard (hazardous). It was shown that the primary target organ for flufenacet is the liver, and secondary one is the thyroid gland. As a result of the conducted analysis, acceptable daily intake of flufenacet for human at the level of 0,004 mg/kg was justified.
Authors and Affiliations
O. O. Novohatska, О. P. Vavrinevych, А. М. Antonenko, V. G. Bardov, S. T. Omelchuk
Keywords
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