HYPERBARIC BUPIVACAINE WITH FENTANYL COMPARED TO HYPERBARIC BUPIVACAINE ALONE FOR SPINAL ANAESTHESIA IN CAESAREAN SECTION
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2017, Vol 4, Issue 33
Abstract
BACKGROUND Providing anaesthesia for caesarean section is one of the most challenging tasks faced by the anaesthesiologist. If we can add a potent opioid like fentanyl to hyperbaric bupivacaine and thus reduce the dose of bupivacaine used without compromising on the analgesic effect, we may be able to reduce the incidence of unwanted side effects of sympatholysis like hypotension. There may also be a prolongation of analgesia. MATERIALS AND METHODS In this prospective double-blind comparative study, 60 parturients were allocated into two groups of 30 each. Group 1 received 1.6 mL of 0.5% of bupivacaine (heavy) with 0.4 mL of preservative-free fentanyl (20 mcg dose). Group II received 2 mL of 0.5% of bupivacaine (heavy). In order to compare the quantitative data, the statistical constants like mean and standard deviation were computed. The quantity of the mean value of the two groups were tested by applying Student’s t-test. RESULTS There was significantly faster onset of action in the bupivacaine (alone) group. Fall in mean arterial pressure in the bupivacaine (only) group was 23.80% (mean) while in the bupivacaine + fentanyl group, it was 15.37% (mean). This was statistically highly significant (p<0.001). The mean duration of analgesia in the bupivacaine only group was 195.67 minutes, whereas in the bupivacaine + fentanyl group, it was 214.03 minutes. This was statistically highly significant (p<0.5). No adverse effects were noticed on the newborn in both the groups. CONCLUSION Intrathecal fentanyl 0.4 mL (20 ug) added to bupivacaine 1.6 mL (8 mg) for spinal anaesthesia in caesarean section enhances the quality of intraoperative analgesia provides better haemodynamic stability and prolongs the duration of postoperative analgesia without affecting the newborn’s clinical status.
Authors and Affiliations
Archana L. R, Nadarajan Veena
Keywords
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- EP ID EP218699
- DOI 10.18410/jebmh/2017/380
- Views 105
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