HYPolIPIDEMIC ACTIVITY oF CASSIA ToRA SEEDS IN HYPERlIPIDEMIC RATS
Journal Title: Era's Journal of Medical Research - Year 2014, Vol 1, Issue 1
Abstract
The hypolipidemic activity of Cassia tora (Chakvat, Chakunda) (Family: Caesalpiniaceae) seeds extract has been studied in two hyperlipidemic models of rat. These are triton injected and cholesterol rich HFD fed model of hyperlipidemia. In triton WR-1339 induced hyperlipidemia, feeding with root extract (500 mg/ kg body wt/ day p.o. ) exerted lipid lowering effect as assessed by reversal of plasma levels of total cholesterol (TC), phospholipids (PL), triglyceride (TG) and reactivation of Post Heparin Lipolytic Activity (PHLA) of plasma. The other model was fed with cholesterol rich HFD and seeds extract of Cassia tora (500 mg/ kg body wt/ day p.o.) simultaneously for 30 days. This also caused lowering of lipid levels in plasma and liver homogenate and reactivation of plasma post heparin lipolytic activity, hepatic total lipoprotein lipase activity. The hypolipidemic activity of Cassia tora seeds was compared with a standard drug guggulipid (200 mg/ kg body wt/ day p.o.), a known lipid lowering drug in both models.
Authors and Affiliations
Dr. Vishnu Kumar Awasthi, Dr. Brijesh Rathore, Sharique Ahmad, Farzana Mahdi, Ramesh Chander, Ashok Kumar Khanna, Jitendra Kumar Saxena, Abbas Ali Abbas Ali Mahdi, Pradyumn Singh, Raj Kumar Raj Kumar Singh
A CASE OF PARTHENIUM DERMATITS IN A MIDDLE AGED FEMALE
Parthenium dermatitis is an immuno-inflammatory disease caused by Partheniumhysterophorus and is the most common cause of plant dermatitis in India. Contact sensitivity to parthenium is everlasting, and hence the disease...
RHEUMATOID ARTHRITIS : AN UNDERSTANDING IN THE LIGHT OF HERBAL MEDICINES
Rheumatoid arthritis (RA) is characterised by chronic polyarticular synovial inflammation and progressive erosion of cartilage and bone. The disease occurs at any age, but is common among those aged between 40-70 years....
CLINICAL ANATOMY BY REGIONS: RICHARD S SNELL
Basic knowledge of anatomy is essential to interpret the clinical observations as they put their hands or look at the patients. It is the department of anatomy where they learn basic medical vocabulary that they carry th...
THYROID STIMULATORY HORMONE (TSH) REFERENCE RANGES IN THE NORMAL PREGNANT WOMEN OF LUCKNOW
Maternal hypothyroidism is known to be associated with adverse perinatal outcomes. This study was done to evaluate the normal reference range of TSH in pregnant women. 483 pregnant women on their first visit to Obstetric...
RECENT ADVANCES IN HISTOPATHOLOGY: 23
The knowledge of pathology is a constantly emerging specialty. To reflect this, there is a great need to know and review the prompt development and implementation of molecular techniques to support the morphological asse...