Hypomagnesemia As A Link to Dyslipidemia in Diabetes Mellitus
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 5
Abstract
Aim and Objectives: To observe the association between magnesium and lipid parameters in type 2 diabetic patients. Materials and methods: A case-control study consisted of control group (36 healthy individuals) and case group (50 patients who were diagnosed with type 2 diabetes). Serum magnesium and lipid profile wereanalysed in blood samples on automated analyser. The data was analysed using unpaired‘t’ test if the data is normally distributed and Mann-Whitney U test if the data is not normally distributed. Spearman correlation analysis was done. Results: In the present study, a significant low serum magnesium levels (p<0.01) in case group was observed when compared to control group. A significantly higher triglycerides levels (p<0.05), increased TC/HDL ratio levels (p<0.001)and increased Atherogenic index of plasma (p<0.001) was observed in casesgroup when compared to control group. The fasting blood sugar and HbA1C showed statistically significant increase in cases than controls. A negative correlation was observed between magnesium and cholesterol (r = -0.3, p<0.006), magnesium and LDL (r = -0.2, p=0.03), magnesium and total cholesterol/HDL ratio (r = -0.2, p=0.04). Conclusion: Dyslipidemia observed in Type 2 Diabetes could be due to Hypomagnesemia.
Authors and Affiliations
N. Manaswini, M. Noorjahan, K. S. S. Sai Baba, Priscilla Abraham chandra
Keywords
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- EP ID EP597341
- DOI 10.9790/0853-1605053336.
- Views 78
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