Immunity against Pasteurella multocida in Animals Vaccinated with Inactivated Pasteurella multocida and Herbal Adjuvant ‘DIP-HIP’
Journal Title: Journal of Vaccines and Immunology - Year 2016, Vol 2, Issue 1
Abstract
Background: Haemorrhagic septicaemia (HS) is acute, highly contagious form of disease of water buffalo, cattle, and bison caused by Pasteurella multocida (PM). It is considered the most economically important bacterial disease of cattle and buffalo, .in tropical areas of Asia, particularly in Southeast Asia. PM is a gram-negative coccobacillus, belonging to Pasteurellaceae family. PM is transmitted either during direct contact or via fomites by ingestion or inhalation via contaminated feed and water. Currently, there are no broadly protective vaccines –adjuvant formulation with long-lasting immunity available against HS. Aluminium-based mineral salts such as alum are the only immunologic adjuvants. Herbal adjuvants are evaluated extensively to replace the classical adjuvants being safe and efficacious.
Authors and Affiliations
Tanwar Himanshi, Yadav Anand Prakash, Brijbhushan B, Shweta S, Singh Shashi Bala, Ganju Lilly
Keywords
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- EP ID EP553746
- DOI 10.17352/jvi.000014
- Views 55
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