Immunotherapy in Prostate Cancer
Journal Title: Üroonkoloji Bülteni - Year 2019, Vol 18, Issue 2
Abstract
In recent years, immunotherapy has become an important treatment alternative in the treatment of many cancers. Research on immunotherapy in prostate cancer has been accelerated by obtaining Food and Drug Administration (FDA) approval of sipuleucel-T for asymptomatic or minimal symptomatic metastatic castration-resistant prostate cancer (CRPC). Despite all these developments, the patients in whom these agents should be used, sequential use and combination strategies remain unclear. In this review, mechanisms of action and survival outcomes of different immunotherapeutic agents and therapeutic cancer vaccines in mCRPC are discussed.
Authors and Affiliations
Deniz Bolatq, Ayfer Haydaroğlu
Socioeconomic Predictors and Patient Perspectives of Prostate-specific Antigen Testing
Objective: To identify important factors affecting men’s decision to undergo prostate-specific antigen (PSA) testing and to determine who is at risk for prostate cancer based on age-specific PSA values. Materials and Me...
Do the Pain Scores During Transrectal Ultrasound-guided Prostate Rebiopsy Change in Patients with a Prior History of Prostate Biopsy?
Objective: In this study we evaluated the effects of prior history of prostate biopsy on pain scores of patients who underwent transrectal ultrasound-guided prostate biopsy (TRUS-PBx). Materials and Methods: Between Octo...
Initial Outcomes and Assessment of the Transperineal Multiparametric-Magnetic Resonance Imaging/Ultrasonography Fusion Biopsy Method in Diagnosing Clinically-significant Prostate Cancer
Objective: In this study, it was aimed to investigate the success of transperineal multiparametric magnetic resonance imaging (mp-MRI)/transrectal ultrasonography (USG) fusion prostate biopsy method in prostate cancer di...
Transperitoneal Laparoscopic Nephrectomy-Our Initial Experiences
Objective: To evaluate the first experiences of laparoscopic nephrectomy operations performed in our clinics. Materials and Methods: A total of 61 laparoscopic nephrectomy operations were performed in our clinics during...
Do Length and Tumor Grades of Positive Surgical Margin Have an Impact on Biochemical Recurrence After Prostatectomy?
Objective: Biochemical recurrence (BCR) does not occur in all patients with surgical margin (SM) positivity after radical prostatectomy (RP). The aim of our study is to evaluate the effect of additional features such as...