Impact of Calorie Intakes on the Risk of Bronchopulmonary Dysplasia in Extremely Preterm Infants
Journal Title: Archives of Pulmonology and Respiratory Care - Year 2017, Vol 3, Issue 1
Abstract
Aim: To examine whether caloric intake during the first week of age influences the risk of Bronchopulmonary Dysplasia (BPD) in extremely preterm infants. Methods: In this retrospective cohort study, all infants born with gestational age < 29 weeks over 30 months period were eligible for the study. Infants with major congenital anomalies and those who died before 36 weeks postmenstrual age were excluded. We compared the nutritional characteristics between infants with BPD and those with no BPD. Results: Of the 262 eligible infants, 233 were included for the study. A total of 125 infants developed BPD. Infants with BPD were likely to receive higher fluid intake in the first 2 days of age compared to infants with no BPD. After adjusting for gestational age, severity of illness and PDA, higher daily calorie intake, especially higher protein intake was associated with a trend towards lower odds of BPD (OR= 0.91; 95% CI: 0.81-1.01). Delay in reaching full enteral feed was associated with increased odds of BPD (OR= 1.03; 95%CI: 1.00 - 1.06). Conclusions: In preterm infants born at less than 29 weeks, provision of adequate calorie intake; particularly protein, in the first week of life may be associated with decreased risk of BPD.
Authors and Affiliations
Alshaikh Belal, Buddhavarapu Siddartha, Akierman Albert, Lodha Abhay, Sauve Reginald, Soraisham Amuchou
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