Impact of Hyperglycaemia on Myocardial Infarction
Journal Title: International Journal of Interdisciplinary and Multidisciplinary Studies (IJIMS) - Year 2016, Vol 3, Issue 4
Abstract
Hyperglycaemia is encountered in up to 50% of all ST elevation myocardial infarcted (STEMI) patients, whereas previously diagnosed DM is present in only 20% to 25% of STEMI patients.Present study was undertaken to find out the correlation between hyperglycaemia and complications and outcome in patients admitted with acute myocardial infarction in our hospital. Present prospective observational study was conducted on 200 patients admitted to the medical wards in hospital with acute myocardial infarction with or without diabetes mellitus. After a detailed history and physical examination, blood sugar levels,lipid profile, cardiac enzymes,ECG and echocardiogram were performed in all patients. Patients were then divided into 3 group’s i.e. Diabetics, Stress induced hyperglycaemics and non-hyperglycaemics for comparison.Data was analysed using SPSS software ver. 21 usingappropriate statistical tests. Hyperglycemia was observed in 82% of the study subjects, of which 65% were known cases of diabetes, 17% were having stress induced hyperglycemia and 18% were normoglycemics. All the 3 groups were comparable with respect to risk factors like hypertension and dyslipidaemia and complications like cardiogenic shock and heart failure. Poor outcome (i.e. death) was observed in 11.5%, 11.8% and 2.8% of patients with diabetes stress induced hyperglycaemia and non-hyperglycaemics respectively (p> 0.05),but the difference was non-significant. Complaint of angina was found to be significantly lower in diabetics (48.5% vs 67.6% vs 69.4%; p -0.024). Though not significant, but poor outcome was observed with hyperglycaemia irrespective of the diabetic status. We recommend that more studies with larger sample size should be conducted to throw more light on this issue.
Authors and Affiliations
Santosh Gosavi, Kapil Raut
Keywords
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