IMPACT OF TOBACCO, ALCOHOL, AND SMOKING PROPENSITIES IN ORAL PRECANCER WITH HISTOLOGICAL DEMONSTRATED EPITHELIAL DYSPLASIA
Journal Title: Journal of Advanced Medical and Dental Sciences Research - Year 2017, Vol 5, Issue 6
Abstract
Background: Oral epithelial dysplasia (OED) is a histopathological diagnosis that is associated with an increased risk of oral cancer. The main aim of this study is to identify the impact of tobacco, alcohol, and smoking propensities in oral precancer with histological demonstrated epithelial dysplasia. Materials and methods: The examination test included biopsy demonstrated instances of 42 oral submucous fibrosis (OSMF) and 48 instances of clinical leukoplakia. Histopathological analysis was produced using formalin settled paraffin embedded tissues according to WHO criteria. The applicable clinical and statistic points of interest were recorded subsequent to talking the patients. Result: Occurrence of epithelial dysplasia was fundamentally connected with tobacco in OSMF and both tobacco and smoking propensities in leukoplakia. In OSMF tobacco was related with 16 times furthermore, in leukoplakia tobacco was related with 5-overlay and smoking was related with 11 overlap expanded danger of epithelial dysplasia. Conclusion: In this examination, current tobacco smoking was a significant hazard factor for epithelial dysplasia in OSMF patients while previous smokers had an extensively decreased hazard contrasted with current smokers
Authors and Affiliations
Amit Kumar Joseph
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