Implementation and Effectiveness of Six Sigma by Using Dmaic Approach in Pharmaceutical Industry
Journal Title: International Journal of Modern Research In Engineering & Management. - Year 2019, Vol 2, Issue 6
Abstract
six sigma is a systematic approach which follows five basic steps i.e. dmaic (define, measure, analysis, improve & control). all steps are encumbered multiple tools of problem solving, root cause identification and process improving and controlling. the problem of yield loss is also being solved through six sigma methodology. Initially the study is focused on defining the problem, following the process flow, drawing the project boundary in between the process flow to focus on real problem, identification and measurement of the variables which influence the yield. Identified factors are then analyzed to hunt potential causes. Significant improvement in the cause identified resulted in improved sigma level and equipment efficiency, finally the control is built keeping in view the failure mode effective analysis results for standardizing and sustaining the improvement for longer period of time through control charts and fool proof systems. the purpose of this deep dive is to investigate and identify the major potential causes which results in low profit and turnover due to low yield products in a pharmaceutical company. Manufacturing process is a major area of profit generation of pharmaceuticals and play a vital role in achieving the market share. continuous decline of its profit due to yield losses made itself a great challenge. it is identified that on an average there is 1.40% yield loss in every batch. therefore, it is necessary to stop the interruption in the production schedule and at the same time resolve the problem with suitable effective and long-term viable solution. however, six sigma methodologies are applied to resolve the complex level of problems and to have optimum and effective solution to continue smooth flow of production and to reduce the wastages
Authors and Affiliations
Engr. Aziz Ahmed
Keywords
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