Importance of HRCT for prediction of disease activity in pulmonary tuberculosis
Journal Title: MedPulse -International Medical Journal - Year 2017, Vol 4, Issue 7
Abstract
Background: Despite all governmental efforts, tuberculosis (TB) remains a public health problem world-wide with almost 9 million new cases each year and almost 2 million TB related deaths world-wide. Aims and Objectives: Study of Role of HRCT in Predicting the Disease Activity in the patients of Tuberculosis. Material and Methods: This was a cross-sectional study carried out in the department of Radiology at Tertiary health care center in the Patients of Tuberculosis during the 3 Yrs. i.e. January 2014 to January 2016. All the suspected patients of TB who were Advised for HRCT were included into study so in the 3 yrs. duration total there were 850 patients were undergone HRCT. Here the diagnostic efficacy of HRCT was compared in terms of sensitivity and specificity. Result:The majority of the Patients were in the age group of 40-50 i.e. 32.35%, followed by 50-60 -27.65%, >60 -13.53%,30-40-12.35%, 20-30 -10.59%, and <10- 3.53% respectively.The majority of the Patients were Males i.e. 52.71% and Females were 47.29%.Sputum Positive and Negative patients the features on HRCT were; Ill-defined nodules present in 70.59%and 6.93 %,Consolidation 66.84%, 10.08%, Tree- in-bud in 74.87%, 1.89%, Cavity in 40.11% and 6.00%Ground glass opacity in16.04%, 2.10 %, Traction bronchiectasis 16.84 %, 62.82%, Atelectasis 8.02% and 52.94%,Calcified granuloma in 0.27 % and 19.96% and Peribronchial thickening in 50.00% and 16.81 % respectively,Sensitivity of HRCT was 91.98% (95% CI-88.75% to 94.52%), Specificity was 79.83 % (95% CI -75.94% to 83.35). Conclusion:Here the sensitivity of the HRCT was 91.98% and Specificity was 79.83 % were very high so it is a useful tool for diagnosis and treatment purpose specially in sputum negative patients also it identifies the disease activity by various HRCT features so it should be employed in association with sputum.
Authors and Affiliations
Shivraj M Ingole, Swapnil S Ingole, Prashant G Pote, Shilpa Domkundwar
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