Importance of lipid-lipoprotein ratios as a diagnostic tool in metabolic syndrome population
Journal Title: National Journal of Physiology, Pharmacy and Pharmacology - Year 2018, Vol 8, Issue 12
Abstract
Background: Metabolic syndrome (MS) is a constellation of diseases caused by several interconnected cardiometabolic risk factors such as obesity, hypertension, hyperglycemia, and dyslipidemia. Lipid-lipoprotein ratios can be considered as an alternative for identifying individuals with MS. Objectives: The objectives of this study were to compare the lipid profile and lipid-lipoprotein ratios of different groups formed based on the progression of the severity of MS. Materials and Methods: A total of 195 participants who volunteered with the signs of MS were divided into three groups based on the presence of metabolic abnormalities as Group I (with <3 components of MS - control group), Group II (with any three components of MS group), and Group III (with >3 components of MS - severe MS group). Results: Results showed that triglycerides (TG), ratio of TG-to-high-density lipoprotein, and total cholesterol (TC)-to-high-density lipoprotein ratio showed significant difference (P < 0.001) between the groups, whereas the results of high-density lipoprotein and lowdensity lipoprotein-to-high-density lipoprotein ratio were significantly more (P < 0.001) in severe MS in comparison with control and MS. TC showed significant difference (P = 0.004) in MS and severe MS when compared with that of control. Conclusion: Early identification and treatment of individuals with MS is very important to prevent debilitating effects associated with its development.
Authors and Affiliations
Bhagyashree N, Ganesh M, Ramaswamy C
Keywords
Related Articles
- EP ID EP497921
- DOI 10.5455/njppp.2018.8.1031216102018
- Views 78
- Downloads 0
Dynamics of the content of free amino acids in blood of patients during the long-term use of orthopedic dental metal prostheses
Background: The effect of materials for dental prostheses on the patient’s body remains one of the most relevant issues in orthopedic dentistry. The dentist, more often the orthopedist, has to deal with diseases arising...
Effect of family history of hypertension on the autonomic nervous system in normotensive individuals
Background: Hypertension is a major public health problem, which usually has a silent modus operandi. It is the outcome of a complex interaction between genetic and environmental factors. Aims and Objective: The aim of t...
A comparative prospective study to assess the efficacy and safety of iron sucrose versus iron sorbitol citric acid in pregnant women with iron deficiency anemia in a tertiary care hospital
Background: The prevalence of iron deficiency anemia (IDA) is 58% among pregnant women in developing countries. According to the recent national guidelines, intramuscular iron sorbitol citric acid (ISCA) complex is one o...
High-dose cytarabine-associated cerebellar toxicity: A case report
High-dose arabinoside cytarabine is used as an effective regimen for post-remission acute leukemia and refractory leukemia treatment. Most commonly used regimen is 3 g/m2 IV over 1-3 h q12 h for a total of 8-12 doses. M...
Learning to learn and teach: Student seminar as a teaching-learning method in undergraduate medical physiology through students’ perspective
Background: The efficacy of traditional lectures has been debated. Still a predominant form of educational technique, lectures have failed to transfer concepts as effectively as active learning approaches. Innovative tea...