In-silico designing of NKK: A better ligand than Aciclovir against Herpes Simplex Virus
Journal Title: Indian Journal of Pharmaceutical and Biological Research - Year 2015, Vol 3, Issue 1
Abstract
Aciclovir is the best dr thymidine kinase made by the HSV. In the current study we have successfully designed a drug candidate “NKKâ€, which is far more efficient than aciclovir in terms of binding energy and physiochemical properties again used softwares viz. Autodock 4.0, FireDock and Hex dock in order to demonstrate that “NKK†is a better ligand than aciclovir with respect to aforesaid properties.
Authors and Affiliations
Neelabh| Department of Zoology, Mahila Mahavidyalaya, Banaras Hindu University, Varanasi-221005, India, K. K. Jeswara| 2Department of Bioinformatics, Mahila Mahavidyalaya, Banaras Hindu University, Varanasi-221005, India, A. Kumari| Department of Zoology, Mahila Mahavidyalaya, Banaras Hindu University, Varanasi-221005, India, K. Singh| Department of Zoology, Mahila Mahavidyalaya, Banaras Hindu University, Varanasi-221005, India
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