In vitro Anti-coagulant Activity of Dalbergia sissoo Bark
Journal Title: The Journal of Phytopharmacology - Year 2017, Vol 6, Issue 5
Abstract
Dalbergia sissoo belonging to family Fabaceae is a widely growing plant and has been reported to possess multiple therapeutic properties like analgesic, anti-inflammatory, analgesic and antipyretic anti-ulcer, antioxidant, anthelmintic, antimicrobial, antidiabetic and is also used to treat syphilis, dysentery, nausea, eye and nose disorder, skin diseases and blood disorder. However, the plant yet has not been fully elucidated for its anti-coagulant property. Hence, in the present investigation an attempt has been made to explore the anticoagulant potential of Dalbergia sissoo bark in comparison with a known standard drug as the positive control and normal saline as the negative control. The anti-coagulant activity of the aqueous and alcoholic extract of Dalbergia sissoo bark may be due to presence of phytochemicals such as flavonoids and phenolic compounds which reveals on preliminary phytochemical screening.
Authors and Affiliations
Jyoti B . Wadekar, Ramesh L. Sawant, Sachin V. Kirtane, Kunal R. Sanklecha, Amol S. Ghodechor, Bhagyashri B. More, Varsha R. Raut
Pharmacognostic evaluation of selected species of Caralluma genus
Objective: To establish a set of standardized parameters this will assist in identification of raw material of Caralluma species. Materials: The present study reports, detailed set of parameters from four species, Cara...
Antioxidant activity and total phenolic content of some nuts commonly consumed in South-Western Nigeria
Improved health associated with frequent eating of nuts as one of the most unexpected nutritional discovery of the 1990s formed the basis of this study. Hence, the evaluation of some selected nuts commonly consumed as...
Pharmacognostical and analytical study of Kushmanda ghrita, a polyherbal formulation, for pharmaceutical standardization
Kushmanda Ghrita is a unique polyherbal Ayurvedic formulation recommended in the management of various psychological disorders mentioned in Astanga Hridaya and also in Bhaishajya Ratnavali and the formula given is the...
Pharmacological potential of naturally occurring nonstarch polysaccharides (NSP)
Since ancient times, plants have been serving as a promising source of medicines and in recent times, extensive research has been made to isolate, characterize and screen a number of phytoconstituents/secondary plant m...
Antidiabetic potentials of Syzygium guineense methanol leaf extract
This study examines the effects of a methanol extract of Syzygium guineense leaves in streptozotocin (STZ) - induced diabetes, evaluates its effect on alpha glucosidase and 2, 2-diphenyl-1-picrylhydrazyl radical. Diabet...