In vitro Efficacies of Some Nigerian Medicinal Plant Extracts against Toxigenic Aspergillus flavus, A. parasiticus and A. ochraceus
Journal Title: Journal of Pharmaceutical Research International - Year 2016, Vol 9, Issue 1
Abstract
The aim of this work was to find an alternative to chemical fungicides currently used in the control and prevention of activities of toxigenic Aspergillus flavus, A. parasiticus and A. ochraceus in food and feed. The antifungal activity of extracts of five medicinal plants used in native medicine in Nigeria is reported. All plant extracts were screened for their minimum inhibitory concentration (MIC) against toxigenic Aspergillus flavus, A. parasiticus and A. ochraceus. Antifungi efficacies of the medicinal Plant extracts showed that maximum antifungal activity was demonstrated by ethanolic, hot and cold water extracts of Borreria verticillata, Lactuca capenisi, Colocasia esculenta, Jatropha gossy and Ageratum conyzoide. Leaves part of the five medicinal plants were investigated for antifungal activities against toxigenic Aspergillus flavus using radial growth technique. The plant extracts of Borreria verticillata inhibited the growth of the test organisms. Borreria verticillata appears to be more effective as an antifungal agent than other plant extracts. The ethanolic extracts were more effective than the cold and hot water extracts against the tested organism.
Authors and Affiliations
Yemisi Adefunke Jeff-Agboola, Anthony Kayode Onifade
Design, Synthesis, Biological Evaluation and Docking Studies of Some New Diclofenac Analogues
Aim: There is still a need for new, selective COX-2 inhibitors with an improved safety profile, therefore, a series of diclofenac analogues were designed and different physicochemical properties were calculated such as l...
Fenofibrate Potentiates the Antihyperglycemic, Antidyslipidemic and Hepatoprotective Activity of Pioglitazone in Alloxan-Induced Diabetic Rats
Aim: The present research was designed to investigate the hypoglycemic, hypolipidemic and hepatoprotective activity of the fixed dose combination of pioglitazone and fenofibrate. Methodology: For the study purpose, piogl...
Potential for a Beneficial Effect of Theophylline on Extended Acute Inflammation: Review
Inflammation is often prolonged after sepsis, trauma and other acute pro-inflammatory events, particularly above the age of 80 years. Exposure to inflammation of inappropriate amplitude or duration is associated with a h...
Evaluation of the Antioxidant Activities of Psidium guajava and Aloe vera
This paper aimed to study the antioxidant properties of two Nigerian plants Psidium guajava (guava) Myrtaceae and Aloe vera Liliaceae plants which have a broad application in phytomedicine. The plants were assessed by qu...
Evaluation of Effect of Insurance Coverage on Sale Volume and Price of Entered Drugs in Insurance List in 2012 in Iran
Background: Drug industry is considered as the second profitable industry in the world and plays an important role in global economy. The sharp annual growth in drug expenditures imposes heavy loads on the health insuran...