In-vivo Evaluation of Antidiarrhoeal Activity of Ethanolic Extract of Uraria lagopoides (L.)
Journal Title: Scholars Academic Journal of Pharmacy - Year 2014, Vol 3, Issue 6
Abstract
Uraria lagopoides (L.) (Papilionaceae), a trailing perennial herb locally known as ‘Prisniparni’ finds use as a remedy for several ailments. The purpose of the present study was to evaluate scientifically the anti-diarrhoeal effects of Uraria lagopoides used traditionally in Indian system of medicine using castor oil-induced diarrhoea and castor oil-induced enteropooling in rats. The phytochemical studies of the ethanolic extract revealed the presence of flavonoids, glycosides, proteins and phytosterols. The extract showed significant (p< 0.001) protection against castor oil-induced diarrhoea and castor oil-induced enteropooling at (400 mg/kg). The plant extracts exhibited dose dependent antidiarrhoeal effects in the all treated groups and the results were compared with that of loperamide (3mg/kg, p.o) as reference standard drug. Keywords: Uraria lagopoides, Castor-oil, Enteropooling, Anti-diarrhoeal.
Authors and Affiliations
Konda Ravi Kumar, Vijay Kumar Nuthakki
Keywords
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