INCIDENCE OF ACUTE LYMPHOBLASTIC LEUKEMIA, EXPERIENCE AT KING HUSSEIN MEDICAL CENTER (KHMC). JORDAN
Journal Title: European Journal of Biomedical and Pharmaceutical Sciences - Year 2018, Vol 5, Issue 5
Abstract
Aim of the study: To evaluate the incidence of newly diagnosed cases of acute lymphoblastic leukemia, and to examine the relation of ALL incidences with patient's AN. Methods: This is a retrograde statistical study, all data was retrieved from the lab records at the Hematopathology Department / Princess Iman Center for Research and Laboratory Sciences/KHMC over a 6 years period (2008-2014). For each patient's complete blood count, bone marrow aspirate, flowcytometry, and cytogenetic study were performed. Results: Total number of newly diagnosed cases is 94 (including both adults and children), of which 82 cases are B-ALL, 11 cases are T-ALL and 1 case undifferentiated ALL. 92% of cases are in the age group of 1-13 years with the peak in the age group of 2-3 years. Of the 94 cases, males are 54 and females are 40 with an M: F ratio of 1.4:1. 53 patients show no cytogenetic abnormalities; 34 males and 19 females while 41 patients show cytogenetic abnormalities; 20 males and 21 females. Conclusion: incidence of acute lymphoblastic leukemia appeared comparable with global published data. Morphological and cytogenetic findings in association with age and gender revealed that B-ALL more frequently than T-ALL. The peak incidence was in male children 2-3 years age which is keeping with global statistics.
Authors and Affiliations
Ahmad Bani Salameh
Keywords
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