Inflammatory Markers in Hyperemesis Gravidarum
Journal Title: European Archives of Medical Research - Year 2021, Vol 37, Issue 1
Abstract
Objective: This study aims to investigate the role of inflammation in the pathophysiology of hyperemesis gravidarum (HEG). Methods: This prospective study was conducted in the Department of Obstetrics and Gynecology at Near East University Hospital between July 2019 and March 2020. The patients that were defined as HEG should have the following symptoms: Persistent nausea and vomiting, loss of >5% of pre-pregnancy body weight, presence of at least one positive ketonuria test in a random urine analysis, fetal heartbeat positivity at 6-13 weeks of gestation, and singleton pregnancy. Total blood count including white blood cell (WBC), neutrophil (NEU), lymphocyte (LYM), hemoglobin, hematocrit, and platelet and red cell distribution width (RDW) and platelet distribution width were analyzed. NEU-to-LYM (NLR) and platelet-to-LYM ratios (PLR) were calculated. Results: Forty-nine patients with HEG and 121 healthy women were evaluated in the first trimester of pregnancy. The healthy pregnant women and patients with HEG had similar age, gravida, parity, gestational weeks, and body mass index. WBC, NEU, RDW, C-reactive protein (CRP), and urinary ketone levels were statistically higher in the HEG group. There were no differences in terms of NLR or PLR. Conclusion: Measurement of inflammatory markers, such as WBC, NLR, PLR, and CRP levels, might provide valuable knowledge in HEG diagnosis. NLR and PLR are acceptable, but CRP level is a better indicator for predicting the diagnosis and severity of the disease according to our study findings.
Authors and Affiliations
Özlen Emekçi Özay, Ali Cenk Özay
Keywords
Related Articles
- EP ID EP693347
- DOI 10.4274/eamr.galenos.2020.32448
- Views 64
- Downloads 0
Kounis Syndrome as a Result of Anaphylactic Reaction to Gold Dust: A Case Report
Kounis syndrome (KS) is described as the provocation of an acute coronary syndrome through activation of mast cells resulting in allergy, hypersensitivity, anaphylaxis, or anaphylactoid reaction. The case is here present...
Calculation of Embryo/Fetus Dose in Pregnant Thyroid Patients Who Have Accidentally Received Radioiodine
Objective: The aim of this study was to calculate the embryo/fetus dose in pregnant patients who have accidentally received radioiodine (131I) and to evaluate the termination of pregnancy by giving teratological advice t...
A Comparative Study of Two Different Accommodative Intraocular Lenses: The Visual and Accommodative Amplitude Outcomes
Objective: To compare distance and near visual acuity along with accommodative amplitude in eyes implanted with the Tetraflex and the Tek-clear accommodating intraocular lenses (AIOLs). Methods: Comparative, prospective...
Inflammatory Markers in Hyperemesis Gravidarum
Objective: This study aims to investigate the role of inflammation in the pathophysiology of hyperemesis gravidarum (HEG). Methods: This prospective study was conducted in the Department of Obstetrics and Gynecology at...
Rare Extrapulmonary Tuberculosis in Immunocompetent Adults: Experience of a Tertiary Hospital
Objective: Tuberculosis (TB) is an infection that can involve all tissues and organs. Although pulmonary TB (PTB) is more common, extrapulmonary TB (EPTB) is still a major clinical problem. The incidence of EPTB is 35.1%...