Influence of the fetal neuropeptide complex on changes in retinal light sensitivity over time in patients with primary open-angle glaucoma
Journal Title: Офтальмологический журнал - Year 2017, Vol 0, Issue 6
Abstract
Purpose: To investigate the influence of a fetal neuropeptide complex on changes in retinal light sensitivity over time in patients with primary open-angle glaucoma (POAG). Materials and Methods: The study involved 104 patients (192 eyes; age, 52 to 58 years) with medically controlled POAG and diagnosed with stage I, stage II or stage III glaucoma. In patients of the main group, the fetal neuropeptide complex (Cerebrocurine; Pat. of Ukraine №102,957 issued in 2015) was used as an adjunct to conventional hypotensive therapy. All patients underwent eye examination including visual acuity assessment, biomicroscopy, tonometry, and optical coherence tomography. Changes in retinal light sensitivity in patients with POAG were investigated through changes in mean deviation (MD) using automated static perimetry. In both groups, MD was assessed both before and after treatment. Results: After treatment, the incidence of stabilized MD in patients in the main group was significantly higher than in controls (72.5% vs 45.6%, p < 0.05). The highest and the lowest indices of stabilized MD were seen in patients with glaucoma stage I and glaucoma stage III, respectively (84.8% and 51.8%, respectively). Conclusion: In POAG patients, after the use of fetal neuropeptide complex as an adjunct to conventional treatment, the incidence of stabilized average deviation of retinal light sensitivity was statistically significantly (1.59 times) higher than after the use of conventional treatment only.
Authors and Affiliations
N. Panchenko, E. Gonchar, G. Arustamova, A. Pereiaslova, D. Prikhod’ko, M. Friantseva
Keywords
Related Articles
- EP ID EP251798
- DOI -
- Views 131
- Downloads 0
Status of humoral immune factors in peripheral blood of fronto-orbital trauma patients late after surgery with the use of biocomposite
Purpose: To identify the influence of biocomposite on immune system status in front bone trauma (FBT) patients at 9 months or later after surgery involving the use of the composite material. Material and Methods: Twenty...
Relationships of vascular endothelial growth factor (VEGFA) with stage of diabetic retinopathy and disease duration in patients with type 2 diabetes mellitus
Background: As there is currently an epidemic of type 2 diabetes mellitus (T2DM), increasing attention should be paid to diabetic retinopathy (DR), a major complication of the disease which can lead to disability and bli...
Case Report: Solar retinopathy following exposure to reflected sunlight
Background: Radiation damage to the eye is most commonly caused by sunlight. Solar retinopathy is a form of retinal damage that occurs after exposure to solar radiation, with the most common symptoms being reduced vision...
Neuro-ophthalmological symptoms in pituitary apoplexy
Background: Neuro-ophthalmological symptoms in patients with pituitary apoplexy were subjected to analysis. Impaired circulation in pituitary adenoma causes an atypical clinical course of the disease which makes the earl...
Current surgical rehabilitation techniques for patients with total bilateral symblepharon
Purpose: To investigate the efficacy of a three-stage surgical rehabilitation technique for patients with bilateral total symblepharon; the technique has been developed and advanced and is being used at present at the Oc...