INNOVATIVE AND NOVEL STRATEGY: MICROSPONGES FOR TOPICAL DRUG DELIVERY
Journal Title: Journal of Drug Delivery and Therapeutics - Year 2018, Vol 8, Issue 5
Abstract
Microsponge type of drug delivery is the latest technology which has been introduced in topical skin care, drug products to facilitate the controlled release of the active medicament into the skin in order to reduce systemic exposure and control local cutaneous reactions to active drugs. Microsponge can be loaded into a topical route of drug delivery system for the residue of dosage form of skin and thus controlled release drug delivery system is achieved and in return improving the patient compliance by providing target drug delivery system and prolonging dosage intervals. Microsponge is polymeric delivery systems composed of porous microspheres. They are tiny sponge-like spherical particles and posses large porous surface area. Furthermore, they may enhance stability, reduce side effects, improve patient compliance and modify drug release. Microsponges are the polymer-based microspheres system that has the capacity to entrap a wide variety of substances, and can then be incorporated into a different formulation.
COMFA AND COMSIA STUDIES ON 6, 8-DIBROMO–4(3H)-QUINAZOLINONE DERIVATIVES FOR ANTI-BACTERIAL ACTIVITY AGAINST SALMONELLA TYPHIMURIUM
In order to explore the structure – activity relationship of quinazolinone moiety for anti-bacterial activity against Salmonella typhimurium, a series of 4(3H) – quinazolinone derivatives were subjected to Comparative mo...
ANTIBACTERIAL AND ANTIFUNGAL ACTIVITY OF THREE RAMALINA SPECIES
Lichens are an association of a photobiont (an alga or a cyanobacterium) and a mycobiont (a fungus). The lichen genus Ramalina is one of the cosmopolitan lichen genera and is characterized by fruticose thallus. In the pr...
MICROBIAL TRIGGERED COLON TARGETED COMPRESSION COATED TABLETS OF TENOXICAM: FORMULATION AND EVALUATION
The present investigation deals with to formulation and evaluation of colon specific drug delivery system of Tanoxicam by compression coated tablet technique. Tenoxicam, Avicel pH101, HPMC K4M, Guar gum were used as comp...
EFFECT OF PARTHENIUM HYSTEROPHORUS ON OXIDATIVE STRESS IN PANCREATIC TISSUE OF DIABETIC RATS
Increased oxidative stress and decreased endogenous antioxidant defense has been shown to be a prominent and early features in diabetes mellitus. The present study focused on investigating the possible protective role of...
COMPARATIVE STUDY OF CARICA PAPAYA WITH MARKETED PRODUCT FOR THE TREATMENT OF WOUNDS IN DIABETIC RODENTS
Diabetes is an unending situation associated with peculiarly elevated levels of sugar (glucose) in the blood. This chronic illness is also related with the degenerative extended pathological disorders like retinopathies,...