Interleukin-6, Creatine Kinase, and Antioxidant Enzyme Activities following Platelet- Rich Plasma Treatment on Muscle Injury: A Pilot Study

Journal Title: International Journal of Applied Exercise Physiology - Year 2016, Vol 5, Issue 2

Abstract

The aim of this study was to investigate the effect of autologous platelet-rich plasma (PRP) treatment alongside rehabilitation compared with rehabilitation alone on inflammatory cytokine (interleukin-6, IL-6), creatine kinase muscle type (CKM), and antioxidant enzymes (superoxide dismutase, SOD; catalase, CAT) following hamstring injury. This study was a randomised control trial. Participants diagnosed with grade-2 acute hamstring injury (n=16) were divided into 2 groups of PRP treatment with rehabilitation program (PRP-T) and rehabilitation program (CON). Blood samples were collected at baseline, and 2 fortnightly for the various biochemical assessments. Participants were certified to have recovered upon fulfilling return to play (RTP) criteria. Level of IL-6 and the activities of CKM, SOD, and CAT were measured. PRP-T group benefited from earlier time to RTP with significantly lower IL-6 level and CAT activity compared to CON group. There was no significant difference in CKM and SOD activities between the groups, though a trend of lower values in all variables was observed at week 4 compared to week 0. PRP treatment potentially improves muscle healing process by altering both the inflammatory and oxidative responses, hence hastens time to RTP.

Authors and Affiliations

Lingling Lai, Ashril Yusof, Hamid M. S. A, Selina Khoo, A. M Nahar

Keywords

Related Articles

The relationship between flat feet and cavus foot with body mass index in girl students

Background and Aims: The aim of this study was to investigate the relationship between flat feet and cavus foot with body mass index in girl students. Methods: The study population consisted of the Mazandaran University...

The effect of normative feedback on stability and efficacy of some selected muscles in a balancing task

The purpose of the present study was to determine the effects of normative feedback on stability and efficacy of some selected muscles at different task difficulty levels in novice individuals. Thirty participants (age M...

The Effect of Promotional Tools on Conveying Brand Identity from Sport Consumers’ Viewpoint in the Country’s Premier League

The economic environment and business, advertising in sport is one of the ways that most companies to manage the brand, its products and expanding its market in the country. The aim of the present study investigates the...

Investigation of Supplement (Multivitamin plus to Mineral) Usage at Athletes and Non-Athletes Students

The purpose of current study is to determination of supplement consumption at young students. Supplement industry is becoming one of the most revenue at the world. Nowadays revenue of this business is more than billions...

Effects of Combined exergame and conventional exercise to reduce and prevent fall risk among elderly people: A Hypothesis

Background: Falling among old individuals has provoked ceaseless discussion among gerontologists and physical therapists and it is still one of the greatest issues among this population. Loss of the balance and functiona...

Download PDF file
  • EP ID EP567730
  • DOI -
  • Views 185
  • Downloads 0

How To Cite

Lingling Lai, Ashril Yusof, Hamid M. S. A, Selina Khoo, A. M Nahar (2016). Interleukin-6, Creatine Kinase, and Antioxidant Enzyme Activities following Platelet- Rich Plasma Treatment on Muscle Injury: A Pilot Study. International Journal of Applied Exercise Physiology, 5(2), 1-11. https://www.europub.co.uk/articles/-A-567730