Intermittent Fasting: A Potential Effective Strategy for Preventing Obesity and Type II Diabetes Mellitus
Journal Title: Advances in Food Technology and Nutritional Sciences - Open Journal - Year 2018, Vol 4, Issue 2
Abstract
The prevalence of obesity among adults has increased significantly in the past few decades. In the US alone, one in three adults is classified as obese.1 Most commonly, obesity results from an imbalance of limited energy expenditure to compensate for excess energy intake. However, a number of factors have been identified as possible contributors towards the increasing obesity rates worldwide, therefore acting as a multifaceted problem to resolve.2 Obesity is considered a primary contributor towards the development of type 2 diabetes mellitus (T2DM).3 T2DM is characterized by the inability of pancreatic β-cells to produce a sufficient amount of insulin (insulin resistance) in response to necessary levels of glucose uptake. As a result of inhibited insulin secretion, glucose is not taken up into target tissues such as muscle and adipose tissue, leading to elevated blood glucose levels, or hyperglycemia.4,5 Hyperglycemia can subsequently lead to vascular damage and other adverse effects.6
Authors and Affiliations
Sami Dridi
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