Interstitial pneumonia during treatment with rituximab
Journal Title: OncoReview - Year 2015, Vol 5, Issue 1
Abstract
Rituximab (RTX) is a chimeric anti-CD20 antibody. It plays an important role in the treatment of B cell lymphomas and diseases of autoaggression. RTX-induced lung disease is a rare entity, which should be considered in those patients treated with RTX who present with pulmonary disorders with no clear evidence of infection.A 37-year-old woman suffering from CD20-positive DLBCL (diffuse large B-cell lymphoma) received two cycles of the R-CHOP (RTX, cyclophosphamide, doxorubicin, vincristine and prednisone) regimen. After the second cycle of immunochemotherapy, symptoms of interstitial pneumonia occurred. Having excluded all the other causes, it was diagnosed as a complication associated with the administration of RTX.
Authors and Affiliations
Dominika Leś, Anna Polakiewicz-Gilowska, Beata Kaleta, Danuta Starzyczny-Słota, Elżbieta Nowara
Keywords
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