INTRALESIONAL TRIAMCINOLONE ACETONIDE INJECTION AS A TREATMENT OF CHALOZION VERSUS SURGICAL EVACUATION
Journal Title: WORLD JOURNAL PHARMACY AND PHARMACEUTICAL SCIENCE - Year 2019, Vol 8, Issue 11
Abstract
Chalazion is a frequently encountered eyelid problem in the ophtharnic clinic. It is a chronic sterile lipogranulomatous inflammatory lesion caused by retained sebaceous secretion leaking from meibiomion gland or other sebaceous gland into the adjacent stroma. Different modalities are used for treatment of chalazion of them are the surgical evacuation (incision and drainage) and intralesional steroid injection. The aim of the study is to evaluate the efficacy of transcutaneous triamcinolon acetonied injection in the treatment of primary chalazion as compared to surgical evacuation. A hundred patients with primary chalazion were included the study, 50 of them were treated surgically. The other 50 patients treated with transcutaneous intralisional triamcinolone acetonied injection. 40% of the patients treated by transcutaneous intralisional triamcinolon acetonied injection showed resolution and 60% show no resolution. The study showed a relationship between the duration of presentation and resolution after the steroid injection (the shorter the duration the more resolution) with a p-value < 0.0001 which is highly significant. Also, this study showed that there is no relationship between sex, age, site (upper and lower lid) and resolution after steroid injection with a p-value = 0.658, p-value = 0.362, p-value = 0.804 respectively, which are no significant. The 50 patients who underwent surgical evacuation show complete resolution with no differences regarded the sex, age location, duration of presentation. So, surgical incision and curettage remain the most effective method in the treatment of primary chalazion.
Authors and Affiliations
Dr. Ammar Ahmed Muhamed
Keywords
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