Intravenous Thrombolysis with rt-PA in Patients with Acute Ischemic Stroke: Experience of Al-Azhar University Hospitals and Almaadi Military Hospital Stroke Units
Journal Title: The Egyptian Journal of Hospital Medicine - Year 2018, Vol 73, Issue 4
Abstract
<strong>Background</strong>: Ischemic stroke <strong>(IS)</strong> is defined as a focal neurologic deficit of sudden onset and of presumed ischemic origin that lasts at least 24 hours and is not associated with hemorrhage on computed tomography <strong>(CT)</strong> or magnetic resonance imaging <strong>(MRI)</strong> of the brain. About 87% of strokes are <strong>ischemic</strong>, the rest being <strong>hemorrhagic</strong>. Bleeding can develop inside areas of ischemia, a condition known as "hemorrhagic transformation" <strong>(HT). </strong>Definitive therapy within the first few hours is aimed to removing the blockage by breaking the clot down (thrombolysis), or by removing it mechanically (thrombectomy). <strong>Aim of the Work</strong>: was to correlate the safety of recombinant tissue plasminogen activator <strong>(rt-PA)</strong> in acute ischemic stroke <strong>(AIS) </strong>patients in Egypt. <strong>Subjects and Methods</strong>: A number of case series of patients with <strong>AIS</strong> who were treated at Stroke Units of Al-Azhar University Hospitals and Almaadi Military Hospital over a period of <strong>1</strong>years within a time window were reported.<strong> Results</strong>: we observed a statistically significant correlation between <strong>AIS </strong>patients who were treated by thrombolysis in time window and vascular risk factors and many important infrastructure-logistic factors. <strong>Conclusions: </strong>It could be concluded that thrombolytic therapy is a good standard treatment in time window but many barriers in developing countries were found.
Authors and Affiliations
Eman Helal
Keywords
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- EP ID EP584495
- DOI 10.12816/ejhm.2018.15102
- Views 133
- Downloads 0
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