Investigating the Relationship Between Impulsivity and Deficit in Executive Functions of Brain in Patients with Substance Use Disorder
Journal Title: The 1st Annual Meeting of Georgian Center for Neuroscience Research - Year 2020, Vol 2, Issue 20
Abstract
Introduction: In recent years, research into the biological foundations of addiction has attracted the attention of many researchers. Researchers found that substance use is the result of greater activity of the brain behavioral activation system which is in turn associated with impulsivity and risk taking. Neurological factors such as impairment of executive functions are also of great importance. This study aimed to investigate the relationship between impulsive behaviors and deficit in executive functions of brain in addicts. Methods and Materials: This research was a cross sectional study. 120 patients with substance use disorder referred to addiction treatment centers were randomly selected. For data collecting, questionnaires were completed before taking medication. Different functions were measured: impulsivity by Barrat`s Impulsivity Scale, working memory by Memory span test and attention by Stroop test. For data analysis, Pearson correlation was used. Findings: data analysis showed a significant statistical correlation between working memory and attention with impulsivity, but this correlation was in negative direction. Conclusion: Executive functions such as working memory and attention are important structures that play a central role in directing and normalizing behavior. These functions are defined as high-level cognitive processes that are involved in the planning, initiation, and regulation of targeted behavior. Deficit in these structures leads to impulsivity and risk taking behaviors. These findings can help experts for the use of proper methods for prevention and expansion of helpful treatments of addiction.
Authors and Affiliations
Rajabpour Mojtaba, Gohari Ali, Eghbali Ghahyazi Hamid, Sheybani Hosein
Keywords
Related Articles
- EP ID EP677957
- DOI 10.29088/GCNR-2020.48
- Views 194
- Downloads 4
Memory Enhancing Effect after Medial Septum Stimulation is Associated with Changes in Hippocampal Cholinergic and Gabaergic Activity
Many brain disorders cause impairments in learning and memory. These include developmental disorders, as well as diseases of old age such as Alzheimer’s disease. People with these disorders often show changes in the hi...
Innate Fear under Social Hierarchy
Behaviors are controlled by innate and learned mechanisms. Fear is a powerful emotion that greatly influences behaviors across species and can be induced by both innate and learned sensory inputs. In addition, fear-rela...
The Antidepressant-Like Effects of Menthol Via Dopaminergic System Using Forced Swimming Test in a Mice Model
Background and purpose: Antioxidants are known to have protective and beneficial effects in the depression. Menthol is an antioxidant compounds in some plants. On the basis of our knowledge, no scientific study has inv...
Is this the way to Stop some of the Post Traumatic Effects of Brain Injury? Effects of Dextromethorphan on the Neurological Scores and Blood Brain Barrier after a Traumatic Brain Injury in Male Rat
Introduction: Dextromethorphan (DM), a sigma receptor agonist and NMDA receptor antagonist, protects neurons from glutamate excitotoxicity, hypoxia and ischemia, and inhibits microglial activation Therefore, in this stu...
Memantine Improves Social Behavior and Prevents Developmental Retardation in Rats Exposed Prenatally to Valproic Acid
Autism spectrum disorders (ASD) is a group of neurodevelopmental disorders which are characterized by impairments in communication and social interaction, repetitive behaviors and a limited repertoire of interests and...