Investigation on the incidence and risk factors of fetomaternal hemorrhage syndrome in pregnant women in Changsha
Journal Title: Chinese Journal of Blood Transfusion - Year 2022, Vol 35, Issue 10
Abstract
Objective To investigate the incidence and possible risk factors of FMH among pregnant women in Changsha. Methods A total of pregnant women (6~42 weeks of gestation) who underwent prenatal examinations in our hospital from June 2019 to December 2020 were enrolled as subjects. In this study, the modified Kleihauer-Betke (K-B) test was used for preliminary screening and flow cytometry was applied to confirme initially positive samples to evaluate the incidence of FMH and estimate fetal blood loss. The logistic regression analysis was used to study the risk factors of FMH. Results The incidence of FMH in pregnant women was 10.45% (183/1 752), the average volume of fetal blood loss was (2.50±3.87)mL, and 0.11% (2/1 752) of the fetal losed blood > 30 mL. Univariate analysis showed that age, twin pregnancy, pregnancy complicated with uterine fibroids, in vitro fertilization, fetal growth restriction, preeclampsia, and number of pregnancies may be risk factors for FMH. Multivariate analysis showed that twin pregnancy (OR 2.274, 95%CI: 1.135-4.458, P<0.05) and preeclampsia (OR 2.341, 95%CI: 1.082-4.837, P<0.05) were independent risk factors for FMH. Conclusion Maternal age and various physiological and pathological factors during pregnancy may be associated with the risk of FMH, especially twin pregnancy and pre-eclampsia are independent risk factors for FMH.
Authors and Affiliations
Kexin FAN, Penghui ZHU, Yun WANG, Yongjun WANG, Ningjie ZHANG
Keywords
Related Articles
- EP ID EP738375
- DOI 10.13303/j.cjbt.issn.1004-549x.2022.10.009
- Views 57
- Downloads 0
Changes of coagulation function and other indicators of the thawed FFP and FLP at 2-6℃
Objective To observe the changes of coagulation factor activity and protein content of the thawed fresh frozen plasma (FFP) and fresh liquid plasma (FLP) during storage at 2-6℃, and to provide reference for exploring the...
Bibliometrics and visual analysis of platelet rich plasma based on strategic coordinate diagram and co-word analysis
Objective To explore the research status, hot spots and trends of platelet rich plasma (PRP). Methods With "platelet rich plasma (PRP)" and its Chinese equivalent as the subject words, the PRP related articles during Jan...
Correlation between malignant tumors and ABO blood types in Chaoshan area, Guangdong
Objective To investigate the relationship between ABO blood types and the risk of malignant tumors in Chaoshan area, Guangdong. Methods Chi-square test was used to analyze the distribution of ABO blood types between 45 8...
Polymorphism study of HLA-A, B, DRB1 alleles in patients with chronic renal failure, in Shandong Peninsula
Objective To investigate the association between HLA-A, B, DRB1 alleles and chronic renal failure (CRF) in Han population of Shandong Peninsula. Methods Sequence specific oligonucleotide probe-polymerase chain reaction (...
In vitro method establishment for detecting monocyte phagocytosis of sensitized RBCs by flow cytometry
Objective To establish an experimental method for detecting phagocytosis of sensitized red blood cells in vitro by flow cytometry. Methods Mononuclear cells were isolated from the peripheral blood of blood donors and cul...