Invitro alpha amylase effect of Sida acuta Burm
Journal Title: International Journal of Pharmacology and Clinical Research (IJPCR) - Year 2018, Vol 2, Issue 1
Abstract
Introduction Sida acuta is shrub indigenous to pantropical areas, widely distributed in regions and found in pastures, waste lands, cultivated lands, roadsides, lawns and planted forests. Sida acuta is ethanomedically used as treatment of diuretic, asthma, fever, headache, cough, cold, ulcer, anthelmintic, snake bite, urinary disease, female disorders, sedative, eczema, kidney stone, elephantiasis, testicular swelling, poultice for dandruff, rheumatic affections, facial paralysis, pulmonary tuberculosis and gonorrheae. Methods Preparation of hydroalcoholic extract of Sida acuta and Hydro-alcoholic extract of Sida acuta was evaluated for its antidiabetic studies by alpha amylase method. Results The inhibitory concentration (IC50) of Hydro-alcoholic extract of Sida acuta against alpha amylase inhibitory effect was found to be 17.10µg/ml in comparison with acarbose 9.27µg/ml. Hydro-alcoholic extract of Sida acuta showed significant alpha amylase inhibitory effect when compared with acarbose. Hence preparation may be formulated with hydro-alcohol and aqueous extract. Conclusion The present research draws the conclusion that Sida acuta plant showed mild antidiabetic effect, which may be due to the phytoconstituents.
Authors and Affiliations
Krishnaveni A
Keywords
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