Iron deficiency anemia in children with cyanotic congenital heart disease and effect on cyanotic spells

Journal Title: Medical Journal Armed Forces - Year 2018, Vol 74, Issue 3

Abstract

Background: Iron deficiency anemia (IDA) in cyanotic congenital heart disease (CCHD) and its association with cyanotic spells has been documented in literature. However, Indian data especially in the pediatric age group is scarce. This study was conducted to find out the prevalence of IDA in this population. Methods: An observational study was conducted in a tertiary care hospital. Children with CCHD in the age group of birth–12 years were included in the study. Hematological parameters of these patients were determined and compared. An assessment of the incidence of cyanotic spells in the iron-deficient and iron non-deficient children was also done. Data analysis was done using Fischer's exact test. Results: The prevalence of IDA was 47.06% in the study population. The study also showed that hemoglobin and hematocrit levels were paradoxically higher in the iron-deficient group as compared to the non-deficient, though the iron studies revealed the iron deficiency. The incidence of cyanotic spells was higher in the iron-deficient group. The mean corpuscular volume (MCV), red cell distribution width (RDW), serum ferritin, serum iron, total iron binding capacity (TIBC), and transferrin saturation (TS) values were the parameters, which were found to be statistically significant to differentiate the study groups. Conclusion: The prevalence of IDA in children with CCHD was found to be high. Iron-deficient group had an increased frequency of cyanotic spells as compared to the non-deficient group, which was statistically significant.

Authors and Affiliations

Sweta Mukherjee

Keywords

Related Articles

Ultrasound evaluation of cervical lymphadenopathy: Can it reduce the need of histopathology/cytopathology?

Background: The differentiation between the causes of cervical lymphadenopathy is of paramount importance as these have different modalities of treatment with varying prognosis. The aim of this study was to evaluate the...

Loss of a guidewire

Central venous cannulation (CVC) is a common procedure being done in intensive care units (ICU) and operation rooms (OR). It is a safe procedure in the hands of well-trained professionals.

A clinical study to evaluate the results after toric intraocular lens implantation in cases of corneal astigmatism

Backgroud: Modern day cataract surgery aims at a spectacle free vision which becomes difficult in cases with pre-operative astigmatism more than 1.5 D. Implantation of toric intra-ocular lenses (IOL) after phacoemulsific...

Emotional and behavioral disturbances in school going HIV positive children attending HIV clinic

Background: To study the emotional and behavioral disturbances (EBD) in school going HIV positive children attending HIV center in a tertiary care hospital. Method: This cross-sectional study was conducted on 258 HIV inf...

MR Geyser Sign in chronic rotator cuff tears

Acromio-clavicular (AC) joint cysts are rare presentation of chronic shoulder pathology. These cysts may be observed secondary to either degenerative changes in the AC joint with an intact rotator cuff (type 1 cyst) or f...

Download PDF file
  • EP ID EP648748
  • DOI 10.1016/j.mjafi.2017.07.003
  • Views 79
  • Downloads 0

How To Cite

Sweta Mukherjee (2018). Iron deficiency anemia in children with cyanotic congenital heart disease and effect on cyanotic spells. Medical Journal Armed Forces, 74(3), 235-240. https://www.europub.co.uk/articles/-A-648748