Pegylated interferon-α2b and ribavirin decrease claudin-1 and E-cadherin expression in HepG2 and Huh-7.5 cells

Background. Hepatitis C virus (HCV) infection usually results in long-term viremia. Entry of HCV into the hepatocyte requires claudin-1, -6, -9 and occludin. The efficacy of Pegylated interferon-α (PEG-IFN) treatment aga...

Citrus auraptene: A potential multifunctional therapeutic agent for nonalcoholic fatty liver disease

Comparison of prognosis by viral etiology in patients with hepatocellular carcinoma after radiofrequency ablation

[b]Background[/b]. Radiofrequency ablation (RFA) has been performed as a first line curative treatment modality for patients with hepatocellular carcinoma (HCC) within the Milan criteria currently. However, prognosis of...

Evidence for liver injury in the setting of obstructive sleep apnea

Introduction. Obstructive sleep apnea (OSA) and non-alcoholic fatty liver disease (NAFLD) are both strongly associated with obesity. Whether OSA is an independent risk factor for liver injury is uncertain. Objective. To...

IN MEMORIAM-Professor Andrew Burroughs