Is the measurement of the size of uterine lesions with positron emission tomography consistent in pre- and postmenopausal periods in endometrioid-type endometrial cancer?
Journal Title: UNKNOWN - Year 2018, Vol 19, Issue 1
Abstract
Objective: We aimed to investigate the correlation of the size and volume of uterine tumors obtained using positron emission tomography/computed tomography (PET/CT) and pathology specimens in patients with endometrioid-type endometrial cancer (EEC) in the premenopausal period, and to compare the results with those of postmenopausal women. In the premenopausal period, the endometrium uses more glucose than in the postmenopausal period. Therefore, the measurement of uterine tumor size using PET/CT in the premenopausal period may normally be different. Materials and Methods: In this retrospective study, we reviewed the records of patients who were diagnosed as having EEC and underwent hysterectomy. Only patients who underwent preoperative PET/CT imaging were included in the study. The thickness and volume of the uterine lesion, and its maximum standardized uptake value as obtained using PET/CT and hysterectomy pathology specimens were recorded. Results: Tumor size (p=0.051) and volume (p=0.404) were not found to be correlated with the imaging method used in premenopausal women and pathologic specimens. However, there was a correlation in postmenopausal women (p<0.001 for tumor size and p<0.001 for tumor volume). PET/CT has higher sensitivity, specificity, and positive predictive value in the postmenopausal period in the detection of >20 mm uterine tumors. Conclusion: PET/CT has a limited role in the measurement of the size of uterine lesions in all patients, especially in the premenopausal period; therefore, we recommend that frozen-section examinations be used intraoperatively to decide on lymph node dissection.
Authors and Affiliations
Varol Gülseren, Mustafa Kocaer, Özgü Çelikkol Güngördük, İsa Aykut Özdemir, Muzaffer Sancı, Kemal Güngördük
Keywords
Related Articles
- EP ID EP365271
- DOI 10.4274/tjod.64188
- Views 67
- Downloads 0
The effect of the pooling method on the live birth rate in poor ovarian responders according to the Bologna criteria
Objective: Pooling is an alternative method to achieve in vitro fertilization outcomes. This study was to investigate the effect of pooling method on pregnancy outcomes in poor responder patients according to Bologna cri...
How to facilitate laparoscopic extraperitoneal suture?
To show a simplified technique of extraperitoneal laparoscopic suture. Step-by-step explanation of the technique using an educative video and pictures. This technique of extraperitoneal laparoscopic suture is highlighted...
The relationship between semen parameters in processed and unprocessed semen with intrauterine insemination success rates
Objective: To evaluate the relationship between semen parameters and intrauterine insemination (IUI) success rates. Material and Methods: This retrospective study was conducted during a 4-year period (2011-2015) on the m...
Effects of mature cystic teratoma on reproductive health and malignant transformation: A retrospective analysis of 80 cases
Objective: To examine cases of mature cystic teratoma (MCT) that were diagnosed and treated in our clinic regarding their association with fertility, and to detect the rate of malignant degeneration and the types of mali...
An in vitro study on oocyte and follicles of transplanted ovaries treated with vascular endothelial growth factor
Objective Retrieval of high quality follicles and oocytes from transplanted ovaries is essential for higher fertility preservation efficiency. The effect of vascular endothelial growth factor (VEGF) was evaluated on the...