Isolation and Identification of Keratinophilic Fungi from Soil of Gwalior Region and their Control by Methanolic Plant Extracts.
Journal Title: Journal of Biomedical and Pharmaceutical Research - Year 2012, Vol 1, Issue 3
Abstract
Microorganism is ubiquition in nature. A large number of microbes are present in our environment. The human body occurs in dynamic equilibrium with these microbes .infection occurs when a microbe penetrate the body surface of tissues. In these it multiplies and the cumulation effect infects infections damage of disrupt tissues and organs and disease results. In the present study, we found that A. Fumigatus, T. mentagrophyte, T. rubrum. E. Floccosum and chrysosporium sp., A. Niger were the most prevalent keratinophilic fungi found in the soil of Gwalior region, which we have isolated. In vitero evalution was conducted for sensitivity testing with 5 different methanolic plant extracts for the inhibition of hyphal growth and spore formation in A. Fumigatus,, T. mentagrophyte, T. rubrum. E. Floccosum and chrysosporium sp. evalution antifungal activity was carried out by disc diffusion method and well diffusion method. Plant secondary metabolites have been of interest to man for a lon time due to their pharmacological relevance. Higher and aeromatic plant have traditional been used in medicines due to their inhibitory effect on various microbes and they also have antifungal properties .most of their properties are due to essential oil product by their secondary metabolite. Our study shows that fungal infection is common in human being. With the emergence of new effective system and tropical antifungal therapies. Tgere has been greater need search for alternative antifungal agent from microbes or plant. In our study it can be concluded that keratinophilicfungi occurs in the Gwalior region and we have used methanolic plant extracts against fungi. These extracts obtained from plant material [flowers, buds, leaves, twings, bark, herbs, wood, fruits and roots]. They can also be treated against fungi. In this way we have concluded that fresh methanolic plant extracts can be used us antifungal agent as they are found be effective against the test fungi. The ultimate conclusion of this study supports the traditional medicine use of different plant extracts in treating different infections caused by pathogenic fungi in gwalior either by using a single or combined extracts.
Authors and Affiliations
Shilpi Gupta*| BIMR College of Professional Studies, Jiwaji University,Gwalior, M.P., Dr. Alka Mishra| Department of Microbiology, Birla Institute of Professional Studies, Gwalior (M.P.), Anil Kumar Gupta| Research Scholar, Bhagwant University (Ajmer), Institute of Pharmacy & Research Center
Keywords
Related Articles
- EP ID EP1565
- DOI -
- Views 457
- Downloads 49
EVALUATION OF THE SIGNALLING MECHANISMS OF LYSOPHOSPHATIDIC ACID AND ITS ROLE IN THE CENTRAL NERVOUS SYSTEM
Lysophosphatidic acid (LPA), which is proposed to play an important role in normal physiological situations such as wound healing, maintenance of vascular tone, vascular integrity and reproduction, may also be implicated...
EFFECT OF POSTMENOPAUSAL STATUS ON SERUM LIPIDS PROFILE AND URIC ACID IN SUDANESE FEMALES FROM THE GENERAL POPULATION
BACKGROUND: Previous data suggest possible effects of postmenopause on serum lipids profile and uric acid which are established risk factors for cardiovascular system. AIM: to evaluate the changes that may occur on ser...
RELATION OF ANTIOXIDANT STATUS AND LIPOPROTEIN (a) LEVEL IN MYOCARDIAL INFARCTION PATIENTS : A CLINICAL STUDY TO EVALUATE THE ANTIOXIDANT/ LIPOPROTEIN (a) RATIO AS A NOVEL PARAMETER TO INDICATE CARDIOVASCULAR ACCIDENT
Lipoprotein (a), a prominent marker of cardiovascular accident, was first described by Berg in 1963(3). Lipoprotein (a) [Lp(a)] has been considered as one of the distinguished signature in myocardial infarction and for m...
Transdermal Delivery of Bisoprolol Hemifumarate
The aim of this study was to formulate and evaluate the administration of bisoprolol hemifumarate (BH) using transdermal delivery systems. The following formulae were prepared as a reservoir to be used in batch formula...
Pulmonary hypertension; aetio-pathogenesis, current treatment and future prospects
Pulmonary hypertension (PH) is a vascular disorder characterized by pulmonary vascular remodeling and increased pulmonary vascular resistance, ultimately resulting in pressure overload, dysfunction, and failure of the ri...