ISOLATION OF Α-GLUCOSIDASE INHIBITORY ACTIVE COMPOUNDS FROM ETHANOL EXTRACT OF KAYU TUAH (ANTIDESMA CELEBICUM MIQ.) LEAVES
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2015, Vol 6, Issue 1
Abstract
Antidesma celebicum Miq. belongs to Euphorbiaceae family has been used as antidiabetic traditional medicine. The aim of the research was to isolate the α-Glucosidase inhibitory compound from ethanol extract of Antidesma celebicum leaves. The isolation have been done using column chromatography silica gel 60 and the structure was determinated base on spectral data of IR, MS, NMR. The result showed that the isolation obtained gallic acid as α-Glucosidase inhibitor with IC50 value of 0.057 mM.
Authors and Affiliations
Fajar Novi , Elya Berna , Katrin
Keywords
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- EP ID EP158288
- DOI 10.7897/2230-8407.0615
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