Japanese encephalitis epidemiology in Arunachal Pradesh, a hilly state in northeast India
Journal Title: Asian Pacific Journal of Tropical Disease - Year 2011, Vol 1, Issue 2
Abstract
Objective: To confirm Japanese encephalitis (JE) cases from the state of Arunachal Pradesh (AP), India for the first time. Methods: Suspected acute encephalitis syndrome (AES) cases were screened from 2005-2010. The cases were initially tested for antibodies against JE by using IgM MAC ELISA kits (National Institute of Virology, Pune). RNA was extracted from the cerebrospinal fluid (CSF) samples followed by molecular amplification of JE virus specific gene primer. The data obtained were used to calculate relative risks between the age groups and between the genders. Epi info 6.0 was used for the statistical analysis. Results: Presence of JE cases in the state of AP, India was established. JE cases from 10 out of 16 districts were recorded. As part of control and preventive measures, mass vaccination for children (0-15 years) by SA-14-14-2 JE vaccine was taken up in 2010 in the district of Lohit. Vaccination coverage of 83.09% among the target population was achieved. Conclusions: The study presents the first report of confirmed JE cases from the state of AP, India. This finding attracts attention as JE cases are rarely seen to occur in hilly places.
Memory-enhancing activity of Anacyclus pyrethrum in albino Wistar rats
Objective: To explore the potential effect of ethanolic extract of Anacyclus pyrethrum (A. pyrethrum) in memory dysfunction. Methods: Memory impairment was produced by administration of scopolamine (1mg/kg i. p) in rats....
Congenital cytomegalovirus infection: Experience from a tertiary health care centre of North India
Objective: To evaluate the prevalence of congenital cytomegalovirus (CMV) infection in a tertiary health care centre of North India. Methods: In the present study over a period of one year and nine months (January 2011 t...
Impact of floral sources and processing on the antimicrobial activities of different unifloral honeys
Objective: To study in vitro antibacterial activity and physicochemical properties of three unifloral honeys (citrus, clover and cotton honeys), and to study the impacts of storage, dilution with water (33%, w/v) and aut...
A comparison study of Dexmedetomidine Vs Clonidine for sympathoadrenal response, perioperative drug requirements and cost analysis
Objective: To assess and compare the requirement of preanaesthetic agents to maintain anesthesia within the group of control and groups receiving Clonidine and Dexmedetomidine and reduction in cost due to reduced intraop...
Antimalarial potency of the methanol leaf extract of Maerua crassifolia Forssk (Capparaceae)
Objective: To investigate the in vivo antiplasmodial effect of methanol leaf extract of Maerua crassifolia in mice infected with chloroquine sensitive Plasmodium berghei berghei. Methods: The extract was evaluated for ac...