Japanese encephalitis epidemiology in Arunachal Pradesh, a hilly state in northeast India
Journal Title: Asian Pacific Journal of Tropical Disease - Year 2011, Vol 1, Issue 2
Abstract
Objective: To confirm Japanese encephalitis (JE) cases from the state of Arunachal Pradesh (AP), India for the first time. Methods: Suspected acute encephalitis syndrome (AES) cases were screened from 2005-2010. The cases were initially tested for antibodies against JE by using IgM MAC ELISA kits (National Institute of Virology, Pune). RNA was extracted from the cerebrospinal fluid (CSF) samples followed by molecular amplification of JE virus specific gene primer. The data obtained were used to calculate relative risks between the age groups and between the genders. Epi info 6.0 was used for the statistical analysis. Results: Presence of JE cases in the state of AP, India was established. JE cases from 10 out of 16 districts were recorded. As part of control and preventive measures, mass vaccination for children (0-15 years) by SA-14-14-2 JE vaccine was taken up in 2010 in the district of Lohit. Vaccination coverage of 83.09% among the target population was achieved. Conclusions: The study presents the first report of confirmed JE cases from the state of AP, India. This finding attracts attention as JE cases are rarely seen to occur in hilly places.
Correlation of serum paraoxonase activities in known cases of 130 elderly hypertensive South Asian aged 56-64 years - a hospital based study
Objective: To evaluate paraoxonase activity, antioxidant status and lipid peroxidation in hypertensive participants and to address the hypothesis that oxidative modifications of lipids due to hypertension can cause chang...
Comparative in vitro-in vivo correlation analysis with pioglitazone tablets
Objective: To assess the in vitro-in vivo correlation of immediate release formulation of pioglitazone 30 mg film coated tablet. Methods: In vitro release data were obtained for test and reference formulation using the U...
Comparison of chitosan, alginate and chitosan/alginate nanoparticles with respect to their size, stability, toxicity and transfection
Objective: To to compare the chitosan/alginate, chitosan and alginate nanoparticles as plasmid vectors, to determine the morphological characteristics, size and physicochemical properties of nanoparticle-pEGFP complexes...
Limnatis nilotica infestation in ram and kid in Dehloran city, Ilam province, west of Iran
Leech infestation can cause various clinical symptoms in human and animals. There are a few reports about this infestation in the world. In this report, we represented two cases of leech infestation of Limnatis nilotica...
Nanosponges: a potential nanocarrier for novel drug delivery-a review
The ideal delivery system will solubilize the drug, lead the therapy to the target site, and release the therapy to fulfill the individual need of the patient and disease stage. Nanosponges are one of such effective drug...