Japanese Encephalitis Virus: A Summary
Journal Title: International Journal for Research in Applied Science and Engineering Technology (IJRASET) - Year 2017, Vol 5, Issue 7
Abstract
Japanese encephalitis virus (JEV) is a member of Flavivirus genus. It comes under the category of viral brain infection which is spread through mosquito bites. JE virus is transmitted to humans through infected Culex species mosquitoes bite, particularly Culex tritaeniorhynchus. It is most commonly found in areas like South East Asia, the Pacific islands and the Far East. The positive sense single-stranded RNA genome is organized into a nucleocapsid formed by multiple copies of capsid (C) protein arranged in icosahedral, surrounding and anchoring RNA genome. The external envelope is made of envelope protein. It assists in entry of the virus inside of the cell. The genome encodes various nonstructural proteins (NS1, NS2a, NS2b, NS3, N4a, NS4b, and NS5). NS1 is also produced in the secretory form.
Authors and Affiliations
Shagun Shukla
Keywords
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