Lab Diagnosis of Legionnaires’ Disease
Journal Title: Journal of Medical Sciences - Year 2014, Vol 17, Issue 2
Abstract
Legionnaires’ disease is a multi-system disease which causes atypical pneumonia due to Legionella bacteria, most commonly of the species Legionella pneumophila. About one out of every 10 people who get sick from Legionnaires’ disease will die. The most common source of infection-contaminated water supply through inhalation of contaminated water droplets (aerosols). Laboratory diagnosis of Legionnaires’ disease can be made using a variety of laboratory tests including culture/isolation of the causative organism, antigen detection in urine, a significant rise in antibody titers or PCR methods. Determination of the monoclonal subtype and molecular sequence typing can support linking between strains from the sampled environment and from patients. The control measures available to reduce the amount of Legionella in a water system include structural adaptations to the water system, temperature control, disinfection using chemicals or other oxidizing materials, and use of biocides or installation of filters.
Authors and Affiliations
Nayeem-u-din Wani, Aamir Ali
Keywords
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