LARVICIDE AND ANTIFUNGAL ACTIVITIES OF SARSAPARILLA (SMILAX LARVATA) EXTRACTS
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2015, Vol 7, Issue 1
Abstract
Objective: This study aimed to investigate the toxicity, antimicrobial and larvicide activities of Smilax larvata Griseb. (Smilacaceae) extracts.Methods: Toxicity evaluation was performed by testing brine shrimp lethality. The presence of saponins in S. larvata extracts was investigated using a hemolysis test. For antimicrobial investigation, S. larvata extracts were submitted to disk diffusion assay, and larvicide activity was evaluated using a larvicidal assay against Aedes aegypti larvae.Results: S. larvata extracts were not toxic to the shrimp and in the hemolysis test, only hexane, chloroform and ethanolic extracts showed significant hemolytic activity at 1000 µg. mL-1 (100%, 59% and 40% respectively). The crude ethanolic extract presented larvicide effect on third instar of Aedes aegypti larvae with LC50 = 225 µg. mL-1 and LC90 = 350 µg. mL-1, and showed antifungal activity against C. albicans.Conclusion: These results indicate that S. larvata extracts are a potential source of antifungal agents and new eco-friendly larvicide compounds.Â
Authors and Affiliations
Beatriz Cristina Konopatzki Hirota, Cristiane Da Silva Paula Oliveira, Francis José Zortéa Merino, Maria Christina Dos Santos Verdam, Cristiane Bezerra Da Silva, Fabio Seigi Murakami, Obdulio Gomes Miguel, Marilis Dallarmi Miguel
Keywords
Related Articles
- EP ID EP579210
- DOI -
- Views 42
- Downloads 0
MIR-423-3P USED AS REFERENCE GENE FOR MIRNA 146 A IN CELL LINES HEP-G2
Objective: We explored the stable reference genes for miRNA 146 A by RT-PCR in the cell lines Hep-G2 that were treated chlorogenic acid. We must do a series of tests in order to get a reference genes. Based on the litera...
ANTIMICROBIAL RESISTANCE OF PSEUDOMONAS AERUGINOSA STRAINS FROM PATIENTS WITH URINARY TRACT INFECTIONS IN SBMPMC HOSPITAL BIJAPUR, INDIA
Objectives: Urinary tract infections (UTIs) are one of the most common bacterial infections affecting humans throughout their life span. There is paucity of literature in relation to pathogenesis of UTIs caused by Pseudo...
EFFECT OF PIPERINE IN COMBINATION WITH 4-HYDROXYISOLEUCINE ENRICHED TRIGONELLA FOENUM-GRAECUM EXTRACT AND SILYMARIN ON PARACETAMOL INDUCED LIVER DAMAGE IN RATS
Objective: The present study was undertaken to evaluate the hepatoprotective activity of 4-hydroxyisoleucine enriched extract of Trigonella foenum-graecum and silymarin in the presence of piperine, against experimentally...
ANTI-ANXIETY EVALUATION OF EXTRACTS OF STIGMA MAYDIS (CORN SILK)
Objective: The anxiolytic activity of petroleum ether, chloroform and ethyl acetate extracts of Stigma maydis was investigated by Elevated Plus Maze, Hole Board and Mirror Chamber Test.Methods: The study was conducted us...
NON PITTING TYPE PEDAL EDEMA WITH LITHIUM: A CASE REPORT
Objective: To report a case of lithium induced bilateral nonpitting pedal edema.Methods: The clinical data of a bipolar affective disorder patient with current episode of mania and psychotic symptoms who experienced bila...