Latent Toxoplasmosis is Not a Risk Factor for Pregnancy-induced Hypertension
Journal Title: Microbiology Research Journal International - Year 2016, Vol 12, Issue 6
Abstract
Aims: To compare between Toxoplasma IgG antibody seroprevalence in pregnancy-induced hypertensive females (cases) versus normotensive pregnant females (control), and to identify potential risk factors in Toxoplasma infected patients. Study Design: A prospective case-control study. Place and Duration of Study: Outpatient clinics of Obstetrics & Gynecology Department and Department of Medical Parasitology, faculty of medicine, Mansoura University in the period from January 2013 to February 2014. Methodology: We included 78 pregnant females (39 hypertensive, and 39 normotensive; age range 18-39 years). Data concerning demographic and reproductive histories were recorded including previous pregnancies outcome and foetal complications. Comprehensive investigations of the current pregnancy including clinical examination and abdominal ultrasound scan were performed. Five ml venous blood was withdrawn from each female, processed and investigated for the presence of anti-Toxoplasma IgG antibodies by ELISA. Results: The overall Toxoplasma seroprevalence was 40/78 (51.3%) among total participants. Anti- T. gondii IgG antibodies were found in 23/39 (57.5%) of pregnancy-induced hypertension patients and in 17/39 (42.5%) normotensive controls (OR=1.85; 95% CI: 0.7-4.6; P=.17). Of the anti- T. gondii IgG positive patients, 19 (82.6%) had high IgG levels. In comparison only 1 (6.2%) of the anti- T. gondii IgG positive controls showed high IgG levels (P<.0001). Regarding the specific characteristics of Toxoplasma positive pregnancy-induced hypertension patients, none of those characters displayed a significant correlation with hypertensive tendency except history of abortion (P=.004). Conclusion: Chronic toxoplasmosis is not a likely risk factor for pregnancy-induced hypertension although significantly higher titre among hypertensive females necessitates further research.
Authors and Affiliations
A. A. El-Henawy, H. A. El-Nahas, Mostafa M. Alkhiary
Keywords
Related Articles
- EP ID EP350678
- DOI 10.9734/BMRJ/2016/23770
- Views 100
- Downloads 0
Molecular Biology Methods to Assess Microbiological Hazard Concerning Objects of Cultural Heritage
Microorganisms present in the environment pose a considerable hazard to historical objects and works of art. They are capable of settling on objects, and due to their ability to produce various enzymes, they can actively...
Review and Follow up Findings on HIV Serodiscordance among Couples in Benue State Nigeria
Background: Sexual contact with an HIV infected individual is a significant risk in HIV transmission. We observed occurrence of HIV sero-discordance among some couples in our environment and went further to determine the...
Isolation and Identification of Bacteria from Transformer Oil Contaminated Soil
Background: Poly chlorinated biphenyls (PCBs) are organic chemicals with toxigenic, carcinogenic affecting human health and the environment using as dielectric fluids in transformers as a cooling and insulating medium co...
Isolation and Screening of Amylase from Moulds Associated with the Spoilage of Some Fermented Cereal Foods
Aims: The aim of the study is to isolate moulds from spoilt samples of three fermented cereal foods (ogi, eko, pap) and screen the mould for amylase production. Study Design: Primary screening for amylase production by t...
Co-infections; Their Role in HIV Acquisition and Disease Progression
HIV/AIDS disease manifestations play critical roles on the host's immune response to infections especially cell-mediated immunity which is central in combating many other infections, allowing opportunistic pathogens that...