LEUKOGRAM INTEGRAL INDICATORS IN EVALUATION OF HEALTH PIGLETS’ WITH HYPOPLASTIC ANEMIA
Journal Title: ВЕТЕРИНАРІЯ, ТЕХНОЛОГІЇ ТВАРИННИЦТВА ТА ПРИРОДОКОРИСТУВАННЯ - Year 2018, Vol 2, Issue
Abstract
The article deals with the clinical and diagnostic informative value of integral indicators of leukogram for the assessment of health of piglets suffering from aplastic anemia. 18 piglets have been examined: three-week-old - 8 animals (first group), two-month-old - 5 animals (second group), six-month-old - 5 animals (third group). There have been calculated the following leukogram integral indicators: leukocyte index (LI), leukocytal intoxication index (LII), leukocyte shift index (LSI), lymphocytic and granulocytic index (LGI), neutrophil and lymphocyte ratio index (NLRI) and nuclear neutrophil shift index (NNSI) Red blood cells count in three-week-old piglets was Me = 5.65 T/l (5.49 - 6.66) and hemoglobin was Me = 86.0 g/l (76.3 - 89.3); Red blood cells count in two-month-old piglets was Me = 6.71 T/l (6.21 - 7.20) and hemoglobin was Me = 88.0 g/l (84.0 - 89.0); Red blood cells count in two-month-old piglets was Me = 3.41 T/l (2.0-3.6) and hemoglobin was Me = 55.0 g/l (33.0 - 62.0). In the control group of two-month-old piglets red blood cells count is Me = 6.31 T/l (6.16 - 7.30) and hemoglobin is Me = 123 g/l (118.0 - 125.0). In the first group of piglets, LI was 1.46 times higher, LGI - 1.48 times higher; LII - 1.23 times lower, LSI - 1.27 times lower, NLRI - 1.31 times lower, respectively, if compared to the standard indicators. In the second group all the integral indicators of leukogram corresponded to the standard ones. In the third group, LI 1.38 times lower, LII – 1.59 times higher if compared to the indicators of the first group. High LI means that humoral immunity is activated; LGI means that endogenous intoxication is developing; low LII means that the immune system is exhausted due to leukocytopenia, low LSI means that there is active inflammatory process in the body and poor reactivity in the acute run of the disease, low NLRI means that the cells of specific immune defense are dominative. In three-week old piglets the content of total leukocytes in the blood decreased by 56.9% if compared to the control group, two- month-old piglets did not show changes, six-month-old piglets showed an increase by 78.9% if compared to the control group, by 50.9% if compared to the index of the first group, by 86.2% if compared to the indicator of the second group, meaning that the 1st and the 3rd group of piglets have leukocytopenia as an indicator of the poor immunoreactivity of animals with aplastic anemia. Three-week-old piglets suffering from aplastic anemia have the largest changes in the integral indicators of leukogram - LI, LII, LSI, LGI, NLRI if compared to the control group, six-month-old piglets have the largest changes in the integral indicators of leukogram - LI and LSI if compared to the first group, and reflected the development of endogenous intoxication, exhausted immune system and poor reactivity in the acute run of the disease, requiring follow-up examination and pharmacological correction.
Authors and Affiliations
G. S. Kiiko
Keywords
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- EP ID EP454241
- DOI 10.31890/vttp.2018.02.10
- Views 147
- Downloads 0
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