Lipase/Amylase Ratio to Predict Alcoholic Versus Gall Stone as Etiology of Acute Pancreatitis in Population of Upper Assam
Journal Title: PARIPEX-Indian Journal of Research - Year 2016, Vol 5, Issue 12
Abstract
INTRODUCTION: Acute pancreatitis patients are mostly caused by gall stone or chronic alcoholism. Serum Lipase/amylase ratio can be used to distinguish the etiology. AIM: To study serum amylase, lipase, lipase/amylase ratio in patients of acute pancreatitis. METHOD: Prospective study of 549 patients suffering from acute pancreatitis. Blood sample collected in emergency department and subjected to analysis in SEIMENS auto analyser by spectrophotometry. RESULTS: Amylase has positive correlation 0.252, 99% CI with alcoholic pancreatitis with mean lipase/amylase ratio=4.0. In gallstone pancreatitis mean lipase/amylase ratio=1.67. If L/A ratio =2.3, +LR=5.63, –LR=0.17,sensitivity85.7% & specificity84.8%,can be used as cutoff. CONCLUSION: We find Lipase/Amylase ratio of >2.3 suggests alcoholic origin in whom no acute intervention is indicated while ratio< 2.3 of biliary origin in whom surgical intervention required.
Authors and Affiliations
Dr. Arpita Saxena, Dr. Monigopa Das, Dr. Ratnesh Kumar
Keywords
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