Lipid Profile in Metabolic Syndrome Associated with Diabetes, Hypertension, Chronic Kidney Disease and Apparent Health
Journal Title: International Journal of Multidisciplinary Research and Analysis - Year 2022, Vol 5, Issue 10
Abstract
Background: There is dyslipidaemia in metabolic syndrome (MetS). Lipid profiles in MetS associated with different health conditions may not be obvious. This study investigated lipid profiles in MetS associated with type 2 diabetes (DM-MetS), hypertension (HBP-MetS), chronic kidney disease (CKD-MetS) and apparent health (AH-MetS). Methods: 540 patients were recruited for this study; 183 T2D, 136 HBP, 84 CKD patients and 137 AH subjects. They were outpatients and workers in the University of Nigeria Teaching Hospital Enugu. Nigeria. FPG, TC, HDL-C, TG as well as anthropometric measurements were determined using standard methods. Data analyses were done using GraphPad Prism version 2 statistical programme. MetS was diagnosed using NCEP-ATP 111 criteria Results: Study showed 135 DM, 64 HBP, 31 CKD and 52 AH subjects had MetS, (prevalence rates: 36.9 %, 14.7 %, 18.4 %, and 37.9 % respectively). Only 38% MetS subjects had hypertriglyceridaemia while 66% with hypertriglyceridaemia had MetS. Corresponding figures for low HDLC were 40, and 77%. CKD-MetS had higher mean value of TG and TC than others; (2.65 ± 0.16 mmol/l; F = 11.4; P =0.0001; 6.07±0.02mmol/l; p = 0.001). Variations in TC were observed across groups, (p =0.0001). HDL-C was highest in AH-MetS, (1.51 ±0.07 mmol/l) and differed with mean value of DM-MetS, (1.23 ± 0.04mmol/l, p=0.01) only. Following the pattern of TC, LDLC was lowest among DM-MetS, (2.75 ± 0.06 mmol/l) and highest among CKD-MetS, (3.65 ± 0.28 mmol/l, p =0.001) with variations across groups, (F = 6.35; p= 0.0004). Conclusion: Dyslipidemia profile varied with associated disorders. Presence of MetS is not a strong factor for development of lipid disorders in the study population.
Authors and Affiliations
Ogbu, Innocent S. I; Ph. D1, Ogbu Chinemerem C.; B.MLS, Ndukwe, Mbrey; MSc, Agunwah, Elizabeth; MSc, Eze, Clementina MSc , Okeke, Nduka J; FMC. Path
Keywords
Related Articles
- EP ID EP710164
- DOI 10.47191/ijmra/v5-i10-42
- Views 100
- Downloads 0
The Temple as a Tangible Heritage of India: A Living Testament to Culture, Spirituality, and Architecture
The temples of India stand as a remarkable testimony to the nation’s spiritual, cultural, and architectural heritage. This paper delves into the multifaceted role of temples as tangible heritage, tracing their evolution...
Pupils’ Nutritional Status and Their Academic Performance
Nutrition is a fundamental pillar of human life, health, and development across the entire lifespan. This study was undertaken to identify the nutritional status of the pupils and their academic performance; to determine...
The Effect of Board Size, Board Independence and CEO Duality on Firm Value with Financial Performance as A Mediating Variable
This study aims to determine the effect of board size, independent commissioners, CEO duality on firm value with company performance as a mediating variable for corporate governance variables. The number of samples used...
The Right to Freedom: Nepal's Journey through History
This article studies and reviews the historical evolution of the right to freedom in Nepal. It explores the key political events and constitutional developments that have contributed to the formation of the right to free...
The Role of Exercise Therapy in the Prevention and Treatment of Degenerative Hypertension: Literature Review
Human growth and development can be seen from fine and gross motor skills, cognitive abilities, and the maturity of cells in the body. A person's growth and development will reach the peak phase. People have differences...